Second drug targeting KRASG12C shows benefit in mutated non-small-cell lung cancer

Clinical activity with a second drug inhibiting KRASG12C confirms its role as a therapeutic target in patients with advanced non-small-cell lung cancer (NSCLC) harboring this mutation, according to results from a study with the KRASG12C inhibitor adagrasib reported at the European Lung Cancer Virtual Congress 2021. “As we strive to identify the oncogenic driver in more and more of our […]

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Thousands at risk of blindness set to benefit from a new eye drug

Thousands at risk of blindness set to benefit from a new drug that slows vision loss and can even improve sight Brolucizumab approved for patients with wet age-related macular deterioration The painless yet incurable eye disease is leading cause of blindness in over-55s New jab needs to be given only every 12 weeks rather than every single month ThousandsĀ of Britons […]

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Blood test picks out cancers likely to benefit from targeted drugs

A simple and inexpensive blood test could pick out patients with stomach or oesophageal cancer who are likely to benefit from targeted treatment, a new study shows. The test, known as a liquid biopsy, detects cancer DNA in the bloodstream to reveal if stomach and oesophageal cancers are being driven by the presence of too many copies of a gene […]

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Immune properties in ancient DNA found in isolated villages might benefit humanity today

Could remnants of DNA from a now extinct human subspecies known as the Denisovans help boost the immune functions of modern humans? An international study co-led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and published in the scientific journal PLOS Genetics, represents the first characterizations of genes in the DNA of healthy individuals from […]

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Starting estradiol therapy soon after menopause may benefit arteries

Taking estradiol within 6 years after the onset of menopause may help prevent atherosclerosis, plaque buildup in artery walls, from progressing; however, starting estradiol therapy ten years after menopause did not have similar benefits, according to preliminary research presented at the American Heart Association’s Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2020. Estradiol is a female sex […]

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Women older than 75 may not reap death benefit from continued mammography screening

Healthy women over the age of 75 years might not benefit from continuing breast cancer screening. Researchers used data from the Medicare program to estimate the risk of breast cancer mortality under two strategies: continuing versus stopping screening in older women. They found a small mortality benefit for continuing to screen women between the ages of 70 to 74, but […]

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