Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection

These are the findings of a study, published as a research letter in The Lancet, of 51 UK healthcare workers, around half of whom had a previous laboratory-confirmed SARS-CoV-2 infection. It showed that a single dose of Pfizer/BioNTech’s RNA vaccine resulted in a significantly enhanced immune response against the virus, compared to a single dose in those without prior infection. […]

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Research identifies obesity and infection link, as well as treatment found on healthy human skin

The list of diseases and conditions complicated by obesity is a long one; it includes heart disease, cancer, diabetes and impaired wound healing, as well as skin infections. It is not always clear, however, in what way this complication is caused. New research from the School of Pharmaceutical Science at Xiamen University and the Gallo Lab at UC San Diego […]

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Targeting MAPK4 emerges as a promising therapy for prostate cancer

The battle against late-stage prostate cancer might have found a potential new strategy to combat this deadly disease. Research led by Baylor College of Medicine reveals in the Journal of Clinical Investigation that the enzyme MAPK4 concertedly activates androgen receptor (AR) and AKT, molecules at the core of two cellular signaling pathways known to promote prostate cancer growth and resistance […]

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Inhaling statins rather than taking as a pill could end side-effects

Inhaling a lower dose of statins rather than taking them as a pill could end the scourge of side-effects, research suggests Inhaling Statins instead of taking them as a pill could stop common side-effects   Research by University of California, U.S, says this is due to doses being ‘lower’  30 per cent of patients prescribed statins stop taking them due to […]

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WWE Star Gabbi Tuft Has Come Out as a Trans Woman

Retired professional wrestler Gabbi Tuft came out as a transgender woman this week, sharing her identity with the world in a moving open letter to her fans on social media on Thursday. “This is me. Unashamed, unabashedly me,” Tuft wrote in her announcement on Instagram on Friday. “This is the side of me that has hidden in the shadows, afraid […]

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UK vaccination drive expands as virus toll nears 100,000

Britain is expanding a coronavirus vaccination program that has seen more than 6 million people get the first of two doses—even as the country’s death toll in the pandemic approaches 100,000. Health Secretary Matt Hancock said Sunday that three-quarters of the U.K.’s over-80s have received a vaccine shot. He said three-quarters of nursing home residents have also had their first […]

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ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver

Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control. This toxicity has been regarded as a ‘black box’ and is mainly managed by an empirical approach, but there is no clear understanding of the mechanism. Now, researchers from Japan have found that a bit of attention to the types […]

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Germany’s Merkel points to variant risk as infections drop

Germany is seeing a promising decline in new coronavirus infections, but must take “very seriously” the risk posed by a more contagious variant and will have to be cautious whenever it starts easing its lockdown, Chancellor Angela Merkel said Thursday. Merkel and Germany’s 16 state governors on Tuesday decided to extend the country’s lockdown by two weeks until Feb. 14 […]

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