Researchers explore early stages of ribosome formation to identify new targets for antibiotics

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité – Universitätsmedizin Berlin have gained new insights into this multifaceted process. The formation of ribosomal components involves multiple helper proteins which, much like instruments in an orchestra, interact in a coordinated way. One of these helper proteins – protein ObgE – acts as the […]

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Commonly used sweeteners may promote antibiotic resistance

Researchers in Australia have conducted a study showing that commonly used nonnutritive sweeteners can promote the spread of antibiotic-resistant genes in the intestine. The study found that the sweeteners saccharine, sucralose, aspartame, and acesulfame potassium all promoted horizontal transfer of the genes between bacteria in both environmental and clinical settings. The sweeteners accelerated the exchange of antibiotic resistance genes (ARGs) […]

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New insight to Campylobacter sensor structures could lead to targeted antibiotic development

Researchers from the Institute of Glycomics have identified a novel bacterial sensor in Campylobacter species that enable the pathogenic cells to find suitable host cells. The findings have been published in Science Signalling. Campylobacter bacteria are the leading cause of food-borne illness, contributing to enteritis and other gastrointestinal distress we commonly identify as “food poisoning.” About one percent of the […]

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