Forest fires, cars, power plants join list of risk factors for Alzheimer’s disease

A new study led by researchers at UC San Francisco has found that among older Americans with cognitive impairment, the greater the air pollution in their neighborhood, the higher the likelihood of amyloid plaques—a hallmark of Alzheimer’s disease. The study adds to a body of evidence indicating that pollution from cars, factories, power plants and forest fires joins established dementia […]

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Tau protein changes correlate with Alzheimer’s disease dementia stage

Research into Alzheimer’s disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients’ brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain. In new research from their joint laboratory, Judith Steen, Ph.D., and Hanno Steen, Ph.D. show for the […]

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FDA panel reviews 1st new Alzheimer’s drug in 2 decades

One of the biggest drug decisions in decades is looming as U.S. regulators consider whether to approve the first medicine that’s claimed to slow mental decline from Alzheimer’s disease, the most common form of dementia. A panel of outside experts meets Friday to advise the Food and Drug Administration on aducanumab, a drug from Cambridge, Massachusetts-based Biogen Inc. and Japan’s […]

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Dementia: The fruit snack you should eat every week to protect against Alzheimer’s disease

Dementia is the name given to a group of symptoms linked to an ongoing decline in brain function. You could lower your risk of the neurodegenerative condition by regularly eating berries, it’s been revealed. There are a number of different types of dementia, and the most common in the UK is Alzheimer’s disease. Diagnosing the condition early could help to […]

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Scientists eager to explain brain rhythm boost’s broad impact in Alzheimer’s models

The sweeping extent to which increasing 40Hz “gamma” rhythm power in the brain can affect the pathology and symptoms of Alzheimer’s disease in mouse models has been surprising, even to the MIT neuroscientists who’ve pioneered the idea. So surprising, in fact, they can’t yet explain why it happens. In three papers, including two this year in Cell and Neuron, they’ve […]

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Cells study helping to crack the code to Alzheimer’s disease

A study led by researchers at Monash University has opened up new hope for diagnosing and treating Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia in older people and, as there are no effective treatments, is one of the leading contributors to the global disease burden. Various genes have been implicated in the changes that happen in […]

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Many patients with iNPH develop Alzheimer’s disease, too

Up to one in five patients treated for idiopathic normal pressure hydrocephalus, iNPH, also develop Alzheimer’s disease, according to a new study from the University of Eastern Finland and Kuopio University Hospital. The researchers were able to predict the development of Alzheimer’s disease by using the Disease State Index, DSI, that combines patient-specific data from various sources. The results were […]

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Why Didn’t She Get Alzheimer’s? The Answer Could Hold a Key to Fighting the Disease

The woman’s genetic profile showed she would develop Alzheimer’s by the time she turned 50. A member of the world’s largest family to suffer from Alzheimer’s, she, like generations of her relatives, was born with a gene mutation that causes people to begin having memory and thinking problems in their 40s and deteriorate rapidly toward death around age 60. But […]

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