PLD3 gene contributes to risk of Alzheimer’s disease

A rare and controversial mutation in the phospholipase D3 (PLD3) protein—previously linked to Alzheimer’s disease—interferes with PLD3’s vital recycling function inside neurons. Matthew Schrag of Vanderbilt University Medical Center and colleagues report these new findings in a paper published April 8th in PLOS Genetics. About 1 percent of people with Alzheimer’s disease carry a specific mutation in their PLD3 gene. […]

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Alzheimer’s Disease: Everything You Need To Know

In case you didn’t already know, Alzheimer’s is a disease that robs people of their memory. At first, people have a hard time remembering recent events, though they might easily recall things that happened years ago. People with Alzheimer’s might forget their loved ones. They might forget how to dress, feed themselves, and use the toilet. This disease makes the […]

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New study links protein causing Alzheimer’s disease with common sight loss

Newly published research has revealed a close link between proteins associated with Alzheimer’s disease and age-related sight loss. The findings could open the way to new treatments for patients with deteriorating vision and through this study, the scientists believe they could reduce the need for using animals in future research into blinding conditions. Amyloid beta (Ab) proteins are the primary […]

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Increasing glutathione levels lowers Alzheimer’s pathology and improves cognitive decline

Australian researchers have shown that a dietary supplement that increases the levels of a powerful antioxidant in the brain may represent a novel strategy for the treatment and/or prevention of cognitive impairment and debilitating neurodegenerative diseases such as Alzheimer’s disease. Findings of the study were recently published in Neurochemistry International. A team of researchers from UNSW Sydney’s Centre for Healthy […]

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Tony Bennett Has Had Alzheimer’s for More Than 4 Years—But He Hasn't Stopped Performing

Singer Tony Bennett has revealed that he has Alzheimer's disease—in fact, he's had the disease for more than four years. Bennett and his family made the announcement through an in-depth interview with AARP that was published on February 1. Bennett first started experiencing symptoms of his disease in 2015. Initially, he was having trouble remembering musicians' names onstage. Although he […]

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Automated imaging detects and tracks brain protein involved in Alzheimer’s disease

Amyloid-beta and tau are the two key abnormal protein deposits that accumulate in the brain during the development of Alzheimer’s disease, and detecting their buildup at an early stage may allow clinicians to intervene before the condition has a chance to take hold. A team led by investigators at Massachusetts General Hospital (MGH) has now developed an automated method that […]

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Discovery of early plasma biomarkers for Alzheimer’s disease

A Quebec research team has discovered two early plasma markers to detect Alzheimer’s disease five years before its onset. The results of this recent study led by the doctoral student Mohamed Raâfet Ben Khedher and postdoctoral student Mohamed Haddad, directed by Professor Charles Ramassamy of the Institut national de la recherche scientifique (INRS), have been published in Alzheimer’s & Dementia: […]

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Forest fires, cars, power plants join list of risk factors for Alzheimer’s disease

A new study led by researchers at UC San Francisco has found that among older Americans with cognitive impairment, the greater the air pollution in their neighborhood, the higher the likelihood of amyloid plaques—a hallmark of Alzheimer’s disease. The study adds to a body of evidence indicating that pollution from cars, factories, power plants and forest fires joins established dementia […]

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Tau protein changes correlate with Alzheimer’s disease dementia stage

Research into Alzheimer’s disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients’ brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain. In new research from their joint laboratory, Judith Steen, Ph.D., and Hanno Steen, Ph.D. show for the […]

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