Study reveals lower predictive ability for renal cancer models

(HealthDay)—Prospective validation of existing renal cell carcinoma (RCC) prediction models demonstrates a decrease in their predictive ability, according to a study published online June 19 in the Journal of Clinical Oncology. Andres F. Correa, M.D., from the Fox Chase Cancer Center in Philadelphia, and colleagues validated eight RCC recurrence models and the Tumor, Node, Metastasis (TNM) staging system using data […]

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Ability to do pushups may predict cardiovascular risk

World Health Organization (WHO) data indicate that every year there are 17.9 million deaths due to cardiovascular diseases (CVDs), accounting for approximately 31 percent of global deaths. Many of the factors that increase the risk of CVD are modifiable, chiefly an unhealthful diet, a lack of physical activity, smoking, or frequent consumption of alcohol. The link between exercise — particularly […]

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Smoking may limit body’s ability to fight dangerous form of skin cancer

Melanoma patients with a history of smoking cigarettes are 40 per cent less likely to survive their skin cancer than people who have never smoked, according to a new report funded by Cancer Research UK. The study of more than 700 melanoma patients mainly from the north of England—and published today in Cancer Research – provides evidence to suggest that […]

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Researchers identify faulty ‘brake’ that interferes with heart muscle’s ability to contract and relax

Hypertrophic cardiomyopathy (HCM) is the most common genetic disease of the heart and a leading cause of sudden cardiac death in young people and athletes. Scientists have long known that the condition’s cardinal feature—an unusually thick heart muscle that contracts and relaxes abnormally—is fueled by some glitch in the heart’s molecular machinery. Yet, the sparkplug that ignites such disordered muscle […]

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