ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver

Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control. This toxicity has been regarded as a ‘black box’ and is mainly managed by an empirical approach, but there is no clear understanding of the mechanism. Now, researchers from Japan have found that a bit of attention to the types […]

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‘An Arm and a Leg’: For Your Next Health Insurance Fight, an Exercise in Financial Self-Defense

Can’t see the audio player? Click here to listen. A listener asked: ‘How do I remain cool when calling insurance companies?” So we called veteran self-defense teacher Lauren Taylor for advice. She leads Defend Yourself, an organization that works to empower people against violence and abuse.  As Taylor teaches it, self-defense involves a lot more than hitting and kicking. It’s about […]

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A new COVID-19 challenge: Mutations rise along with cases – The Denver Post

The race against the virus that causes COVID-19 has taken a new turn: Mutations are rapidly popping up, and the longer it takes to vaccinate people, the more likely it is that a variant that can elude current tests, treatments and vaccines could emerge. The coronavirus is becoming more genetically diverse, and health officials say the high rate of new […]

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How to stay safe with a new fast-spreading coronavirus variant on the loose

A fast-spreading variant of the coronavirus that causes COVID-19 has been found in at least 10 states, and people are wondering: How do I protect myself now? We saw what the new variant, known as B.1.1.7, can do as it spread quickly through southeastern England in December, causing case numbers to spike and triggering stricter lockdown measures. The new variant […]

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