Mapping the neurons of the rat heart in 3-D

An interdisciplinary team of researchers has developed a virtual 3-D heart, digitally showcasing the heart’s unique network of neurons for the first time. Using the rat heart as a model, the investigators in this study—appearing May 26 in the journal iScience—created a comprehensive map of the intrinsic cardiac nervous system (ICN) at a cellular scale. This map allows for gene […]

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3-D model of human liver for better diagnosis

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3-D structural changes. Researchers at the Max […]

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Computer hardware originally designed for 3-D games could hold the key to replicating the human brain

Researchers at the University of Sussex have created the fastest and most energy efficient simulation of part of a rat brain using off-the-shelf computer hardware. Dr. James Knight and Prof Thomas Nowotny from the University of Sussex’s School of Engineering and Informatics have beaten a top 50 supercomputer by running brain simulations using their own GeNN software and graphics processing […]

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Scientists call for unified standards in 3-D genome and epigenetic data

Studying the three-dimensional structure of DNA and its dynamics is revealing a lot of information about gene expression, expanding our knowledge of how cells, tissues and organs actually work in health and disease. Properly producing and managing this large amount of data is both challenging and necessary for the progress of this field. In a perspective paper published in Nature […]

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