IntroductionGene identification in genetic testingImportance of genetic testingCompanies developing new diabetes technologiesReferencesFurther reading Type II diabetes mellitus (DM) is one of the most common non-communicable diseases. Unlike type I diabetes, in which the production of the hormone insulin is reduced, in type II diabetes, insulin is produced in normal amounts. However, tissue sensitivity to the hormone is reduced. Image Credit: […]

Researchers at Washington University School of Medicine in St. Louis have received a grant from the National Institutes of Health (NIH) to establish a Pediatric Center of Excellence in Nephrology. The center’s physician-scientists will create high-definition molecular reference maps showing genetic details of normal and diseased kidneys during various stages of childhood growth and development. The center’s team also will […]

Despite the pandemic and challenges presented by health inequities and social injustices nationally and worldwide, the 124 students comprising the entering Class of 2022 at Washington University School of Medicine in St. Louis offered hope during their White Coat Ceremony on Friday, Oct. 28, at the Eric P. Newman Education Center. “You give us all hope,” Lisa Moscoso, MD, PhD, […]

La mitad de los votantes dice que la decisión de la Corte Suprema de anular el derecho constitucional al aborto los ha motivado más a acudir a las urnas en las elecciones de medio término que se celebrarán el próximo mes. Y el entusiasmo es aún mayor entre los demócratas y los que viven en estados donde el aborto está […]

Imagine if one day in the future, doctors could diagnose throat cancer, Alzheimer’s, depression or other diseases based on the sound of a patient’s voice. To help make that a reality, Washington University School of Medicine in St. Louis is joining the National Institutes of Health (NIH) Bridge2AI program, an estimated $130 million initiative intended to expand the use of […]

Biomarkers: The precursor to successful liquid biopsy implementationLiquid biopsy in cancer diagnosis and monitoringThe current state of liquid biopsy developmentReferences Further reading  Liquid biopsy refers to the analysis of tumors using biomarkers circulating in several bodily fluids such as the blood. In recent years it has received a large amount of attention in the diagnostic sphere as it presents a minimally […]

IntroductionJones criteria for rheumatic fever diagnosisLaboratory studies for rheumatic fever diagnosisDifferential diagnosisReferences Rheumatic fever represents an autoimmune disease following infection with group A streptococcus (Streptococcus pyogenes), one of the most ubiquitous human pathogens. The disease is characterized by multiple focal inflammatory lesions of the connective tissue structures – particularly of the heart, blood vessels, and joints. Rheumatic fever remains one […]

IntroductionSupporting evidenceEffectsReferencesFurther reading Protein arginylation is a post-translational modification that transfers the amino acid arginine from tRNA directly to protein targets via the enzyme arginyltransferase (ATE1). Arginylation can occur on any residue at the N-terminus of a protein and requires a specific structural recognition motif on the protein surface. Arginylation has an essential role in multiple physiological pathways but remains […]

Congress should crack down on Medicare Advantage health plans for seniors that sometimes deny patients vital medical care while overcharging the government billions of dollars every year, government watchdogs told a House panel Tuesday. Witnesses sharply criticized the fast-growing health plans at a hearing held by the Energy and Commerce subcommittee on oversight and investigations. They cited a slew of […]

A new study from Washington University School of Medicine in St. Louis demonstrates that certain human gut microbes can mine dietary fiber to extract nutrients that otherwise would remain inaccessible to the human body. The study, published June 27 in the journal Cell, illustrates how the fiber byproducts of food production — such as rinds, peels and seeds of fruits […]