Survey shows many primary care doctors are unprepared to help patients avoid diabetes

Which of these is not a risk factor for prediabetes? A) Overweight B) Age 45 or older C) Being white D) Exercise less than three times per week The correct response is C — the actual risk factor being African American, Latino, Native American or Asian American. If you didn’t get it right, don’t feel badly. Chances are your doctor […]

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European guidelines on lipid control advocate ‘lower is better’ for cholesterol levels

Low-density lipoprotein (LDL) cholesterol levels should be lowered as much as possible to prevent cardiovascular disease, especially in high and very high risk patients. That’s one of the main messages of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) Guidelines on dyslipidaemias published online today in European Heart Journal and on the ESC website. Cardiovascular disease (CVD) […]

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For patients with diabetes, ticagrelor reduced heart attacks, strokes: Benefits particularly favorable in patients with prior coronary artery stenting; patients also experienced increased risk of bleeding

In late-breaking clinical trial results presented in a Hot Line Session today at the European Society of Cardiology Congress 2019, investigators from Brigham and Women’s Hospital and Greater Paris University Hospitals — AP-HP/Université de Paris presented the results from The Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study (THEMIS), a clinical trial sponsored by AstraZeneca that […]

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Anxiety, depression linked to more opioid use after surgery

Surgeons wielding their life-saving scalpels, laparoscopic tools, or other implements to repair or remove what ails their patients understand all too well that pain is an unavoidable part of the healing process. Yet the current opioid crisis has made the standard prescribing practices for these highly effective analgesics fraught with risk. New research from Michigan Medicine could help clinicians mitigate […]

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Improving outcomes for sepsis patients

More than 1 million sepsis survivors are discharged annually from acute care hospitals in the United States. Although the majority of these patients receive post-acute care (PAC) services, with over a third coming to home health care (HHC), sepsis survivors account for a majority of readmissions nationwide. Effective interventions are needed to decrease these poor outcomes. A national study from […]

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Athletes at a higher risk for ACL injury after return to sport

Young athletes who do not achieve a 90 percent score on a battery of tests that measure fitness to return to athletic competition, including quadricep strength, are at increased risk for a second knee injury, according to research presented at the Annual Meeting of the American Orthopedic Society of Sports Medicine. Orthopedic surgeons and sports medicine professionals have established return-to-sports […]

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Mutant bacterial receptor could point to new therapies against opportunistic pathogen

Researchers have developed a new mutant version of a receptor used by a bacterial pathogen for a chemical communication process called quorum sensing, according to a study published June 13 in the open-access journal PLOS Pathogens by Bonnie Bassler of Princeton University, and colleagues. As the authors note, the mutant receptor could be used to identify therapeutic compounds that inhibit […]

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Smartphone relaxation app helps some manage migraine

Migraine sufferers who used a smartphone-based relaxation technique at least twice a week experienced on average four fewer headache days per month, a new study shows. Developed in part by researchers at NYU School of Medicine, the app, called RELAXaHEAD, guides patients through progressive muscle relaxation, or PMR. In this form of behavioral therapy, patients alternately relax and tense different […]

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Which brain hemorrhage patients have treatable underlying conditions

When blood vessels in the brain rupture, or hemorrhage, and cause a stroke, large areas of the brain can be permanently damaged. Depending on the cause, some brain hemorrhages may hide underlying lesions that can be treated with surgery, embolization, radiation, or other treatments. Using MRI scans of patients diagnosed with intracerebral hemorrhage, clinical researchers at Jefferson have teased apart […]

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Microbes on explanted pedicle screws: Possible cause of spinal implant failure

Pedicle screws are often used to secure surgically implanted hardware to the spine in patients with spinal disease or spinal trauma. In some cases, these screws loosen over time, leading to spinal instability and consequent pain. This is a common complication of spine surgery. One reason suggested for pedicle screw loosening is implant-associated infection, but until now there has been […]

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