Screening mammography could benefit men at high risk of breast cancer

Selective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a landmark study published in the journal Radiology. Breast cancer in men is a rare but often deadly disease. The American Cancer Society projects that 2,670 new cases of invasive breast cancer will be diagnosed in […]

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Ovarian cancer patients undertested for mutations that could guide clinical care

Fewer than a quarter of breast cancer patients and a third of ovarian cancer patients diagnosed between 2013 and 2014 in two states underwent genetic testing for cancer-associated mutations, according to a study by researchers at the Stanford University School of Medicine and several other organizations. The findings indicate that substantial gaps exist between national guidelines for testing and actual […]

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Levothyroxine treatment in women with thyroid antibodies may not increase live birth rate

Treating women with thyroid antibodies but a normal thyroid function with a medicine called Levothyroxine does not make them more likely to deliver a live baby, new research led by the University of Birmingham suggests. The research, which was led by researchers from the Institute of Metabolism and Systems Research, Birmingham Clinical Trials Unit, the Institute of Applied Health Research, […]

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Excess hormones could cause a condition that can lead to blindness in women, study finds

Research led by the University of Birmingham has found that increased levels of hormones including testosterone could cause a brain condition that can lead to blindness in women. Idiopathic Intracranial Hypertension — also known as IIH — is caused by high pressure in the brain with consequences from blindness to incapacitating daily long-term headaches. IIH was originally identified over 100 […]

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A new method for developing artificial ovaries

An interdisciplinary team of researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) led by Prof. Aldo R. Boccaccini from the Chair of Materials Science (biomaterials) and Prof. Dr. Ralf Dittrich from the Department of Obstetrics and Gynaecology at Universitätsklinikum Erlangen have taken an important step towards developing artificial ovaries for patients suffering from cancer. Together, they have been researching innovative techniques for restoring […]

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New imaging tools that trace key breast cancer enzymes may help guide therapies: Researchers use ‘radiotracers’ to measure PARP-1 and glutamine in breast cancers

A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target important enzymes fueling a range of subtypes, including BCRA-mutated and triple negative cancers. New research from two studies conducted by researchers at the Perelman School of Medicine at the University of Pennsylvania, are presented on today at the […]

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Unraveling a rare mutation to support healthy growth and development

What would happen if you suddenly stopped growing at age 12 or 13? Solving genetic growth mysteries and scheduling regular appointments with pediatric endocrinologists is atypical for most parents and pediatricians. However, for children with growth disorders — a classification that typically describes children below the third or above the 97th percentile of growth charts for their age — receiving […]

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Small risks may have big impact on breast cancer odds of childhood cancer survivors

St. Jude Children’s Research Hospital researchers have evidence that common genetic variations can help to identify pediatric cancer survivors who are at increased risk for developing breast cancer while relatively young. The findings appear today in the journal Clinical Cancer Research. The research focused on the combined effect of 170 common genetic variations that individually confer a modest increased risk […]

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