Uganda begins largest trial of experimental Ebola vaccine

Researchers in Uganda are launching the largest-ever trial of an experimental Ebola vaccine that is expected to be deployed in neighboring Congo, where a deadly outbreak has killed over 1,800 people. The trial of the Janssen Pharmaceuticals vaccine involves up to 800 people and is supported by Doctors without Borders and the London School of Hygiene and Tropical Medicine. Pontiano […]

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Conspiracy theories and fear of needles contribute to vaccine hesitancy for many parents

Over 1,160 cases of measles have been confirmed in the U.S. in 2019. That is more measles cases in just seven months than any full year this decade, and, more problematically, more than all U.S. measles cases from 2010-2013 and 2015-2017 combined. Lawmakers in some states, such as Washington and New York, are already stepping in to combat the outbreak […]

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Targeted interventions raise HPV vaccine acceptance in women

(HealthDay)—Among young women, targeted educational interventions, particularly educational videos, increase human papillomavirus (HPV) vaccine acceptability and knowledge, according to a study published online July 9 in Obstetrics & Gynecology. Lori Cory, M.D., from the University of Pennsylvania and the Fox Chase Cancer Center in Philadelphia, and colleagues conducted an exploratory investigation to discover baseline acceptance of the prophylactic HPV vaccine […]

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Novel model for studying intestinal parasite could advance vaccine development

The intestinal parasite Cryptosporidium, which causes a diarrheal disease, is very good at infecting humans. It’s the leading cause of waterborne disease from recreational waters in the United States. Globally, it’s a serious illness that can stunt the growth of, or even kill, infants and young children. And people with compromised immune systems, such as those with HIV/AIDS, are also […]

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A stomach bug vaccine for babies may cut their diabetes risks

A vaccine against diabetes? Drops that protect babies from a stomach bug cuts risks for the chronic disease by one third, study finds Every year, 17,900 children and young adults under 20 are diagnosed with type 1 diabetes in the US  The number of children diagnosed with the chronic disease fell after the introduction of the rotavirus vaccine The Centers […]

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WHO urges broader use of Ebola vaccine as DR Congo case numbers climb

The World Health Organization on Tuesday urged a dramatic broadening of Ebola vaccination in the Democratic Republic of Congo, where the latest outbreak of the virus has killed more than 1,000 people. More than 111,000 people have already received the protective jab, through a so-called ring vaccination approach aimed at immunising every person who has been in contact with the […]

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New research reviews the state of vaccine safety science

A new systematic review provides a succinct summary of the scientific evidence for and/or against causal associations for 47 adverse events following immunization (AEFI). Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2019 Meeting, taking place on April 24—May 1 in Baltimore. “Health care providers desire objective and clear information on a broad range of […]

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HPV vaccine coverage is far behind other infant vaccines in many US states

Despite the increasing trends in uptake, the human papillomavirus (HPV) vaccine coverage is far behind other infant vaccines in many states, according to a new study, which describes the trends in HPV vaccine uptake in children in the U.S. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2019 Meeting, taking place on April 24—May 1 […]

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Gene-editing technique opens door for HIV vaccine

The human body cannot naturally defend itself against HIV—not usually, at least. But in very rare cases, infected individuals generate broadly neutralizing antibodies, or bNAbs, that fight the virus. Now, Rockefeller scientists have devised a way to grant this HIV-fighting power to otherwise average immune cells. Michel C. Nussenzweig, whose work on bNAbs has produced new HIV treatments showing promise […]

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Exemptions surge as parents and doctors do ‘Hail Mary’ around vaccine laws

At two public charter schools in the Sonoma wine country town of Sebastopol, more than half the kindergartners received medical exemptions from state-required vaccines last school year. The cities of Berkeley, Santa Cruz, Nevada City, Arcata and Sausalito all had schools in which more than 30 percent of the kindergartners had been granted such medical exemptions. Nearly three years ago, […]

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