FDA gives first Ebola vaccine for adults the green light

(HealthDay)—The first Ebola vaccine approved by the U.S. Food and Drug Administration is a single-dose injection called Ervebo. The vaccine from Merck & Co. is approved to protect against the Zaire ebolavirus in people ages 18 years and older. In the United States, Ebola infections are rare. Confirmed cases have involved people in other countries who became infected and then […]

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Rectal microbes influence effectiveness of HIV vaccine

Microbes living in the rectum could make a difference to the effectiveness of experimental HIV vaccines, according to researchers at the University of California, Davis. The work is published Dec. 11 in the journal mSphere. Evidence from human and animal studies with other vaccines suggests that Lactobacillus supplements can boost production of antibodies, while treatment with antibiotics can hamper beneficial […]

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Initial reports suggest new dengue vaccine safer than prior vaccines

A team of researchers at Takeda Vaccines has announced the results of the first phase of trial testing a new vaccine to prevent dengue infections. In their paper published in The New England Journal of Medicine, they outline their trial and how well the drug is working in test cases. The dengue virus infects hundreds of millions of people every […]

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Researchers partner in vaccine project to tackle major killer of African children

A team of University of Otago researchers is part of a major new international vaccine research project to help tackle devastating Salmonella bloodstream infections which are killing thousands of people in sub-Saharan Africa each year. The recently-launched Vacc-iNTS research project aims to advance the clinical development of an innovative vaccine against invasive non-typhoidal salmonellosis. This is an emerging neglected infectious […]

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Uganda begins largest trial of experimental Ebola vaccine

Researchers in Uganda are launching the largest-ever trial of an experimental Ebola vaccine that is expected to be deployed in neighboring Congo, where a deadly outbreak has killed over 1,800 people. The trial of the Janssen Pharmaceuticals vaccine involves up to 800 people and is supported by Doctors without Borders and the London School of Hygiene and Tropical Medicine. Pontiano […]

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Conspiracy theories and fear of needles contribute to vaccine hesitancy for many parents

Over 1,160 cases of measles have been confirmed in the U.S. in 2019. That is more measles cases in just seven months than any full year this decade, and, more problematically, more than all U.S. measles cases from 2010-2013 and 2015-2017 combined. Lawmakers in some states, such as Washington and New York, are already stepping in to combat the outbreak […]

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Targeted interventions raise HPV vaccine acceptance in women

(HealthDay)—Among young women, targeted educational interventions, particularly educational videos, increase human papillomavirus (HPV) vaccine acceptability and knowledge, according to a study published online July 9 in Obstetrics & Gynecology. Lori Cory, M.D., from the University of Pennsylvania and the Fox Chase Cancer Center in Philadelphia, and colleagues conducted an exploratory investigation to discover baseline acceptance of the prophylactic HPV vaccine […]

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Novel model for studying intestinal parasite could advance vaccine development

The intestinal parasite Cryptosporidium, which causes a diarrheal disease, is very good at infecting humans. It’s the leading cause of waterborne disease from recreational waters in the United States. Globally, it’s a serious illness that can stunt the growth of, or even kill, infants and young children. And people with compromised immune systems, such as those with HIV/AIDS, are also […]

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A stomach bug vaccine for babies may cut their diabetes risks

A vaccine against diabetes? Drops that protect babies from a stomach bug cuts risks for the chronic disease by one third, study finds Every year, 17,900 children and young adults under 20 are diagnosed with type 1 diabetes in the US  The number of children diagnosed with the chronic disease fell after the introduction of the rotavirus vaccine The Centers […]

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