Insight into cells’ ‘self-eating’ process could pave the way for new dementia treatments

Cells regularly go through a process called autophagy—literally translated as ‘self-eating’ – which helps to destroy bacteria and viruses after infection. When it works, this process counteracts neurodegenerative conditions such as dementia and Huntington’s Disease, by getting rid of unwanted proteins and their resultant harm to cells. But when autophagy fails or defects occur, it can give rise to such […]

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Blood cancer’s Achilles’ heel opens door for new treatments

New findings about a fatal form of blood cancer could aid the development of new drugs with significantly less harmful side effects than existing chemotherapy. The discovery could lead to novel treatments that efficiently eliminate blood cancer cells in acute myeloid leukaemia (AML), without harming healthy blood cells. Researchers have discovered how a protein in the body plays a key […]

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Analyzing colon cancer proteins and genes uncovers new potential treatments

Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible new therapeutic strategies. This multidisciplinary and multi-institutional study led by researchers at Baylor College of Medicine and published in the journal Cell, strongly […]

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New CRISPR tool executes multiple edits simultaneously, leading to unique partnership to deliver cancer treatments

Scientists at Christiana Care Health System’s Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal. The tool can rapidly reproduce, in a human DNA sample, the unique […]

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