Media overrepresent drug treatments for chronic pain

Media reports on chronic pain are focusing on treatments involving opioids and cannabis at the expense of best practice non-drug treatments, researchers have found. Chronic pain, defined as persistent or recurring pain present for more than three months, is the leading cause of disability worldwide and affects one in five New Zealanders. The researchers analyzed 240 news articles on chronic […]

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Harnessing biology and technology to develop new depression treatments

New research into the biology of depression, along with new and evolving technologies, provides the basis for developing the next generation of treatments for major depressive disorder (MDD), according to the special January/February issue of Harvard Review of Psychiatry. “By embracing a multifactorial understanding of MDD, by attending carefully to the sex difference in its prevalence and manifestation, and by […]

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Brain tumor organoids may be key to time-sensitive treatments for glioblastomas

Lab-grown brain organoids developed from a patient’s own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it. A new study in Cell from researchers at Penn Medicine showed how glioblastoma organoids could serve as effective models to rapidly test personalized treatment strategies. Glioblastoma multiforme (GBM) remains the most difficult […]

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Blood test can quickly match advanced breast cancer patients to targeted treatments

A blood test can help identify rare mutations in advanced breast cancer, which may enable patients to access effective treatments more quickly in the future, Cancer Research UK scientists have found. As part of the plasmaMATCH clinical trial, funded by Stand Up To Cancer, a joint fundraising campaign from Cancer Research UK and Channel 4, the researchers were able to […]

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Breast cancer breakthrough as blood test can quickly match treatments

Smart blood test can identify whether women with aggressive breast cancer will respond to precision drugs, study finds The test detects traces of DNA in the blood that has been shed by the tumour The ‘liquid biopsy’ could save many from having painful tissue biopsies It was 95 per cent accurate, according to the study of 1,000 women  A smart […]

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Insight into cells’ ‘self-eating’ process could pave the way for new dementia treatments

Cells regularly go through a process called autophagy—literally translated as ‘self-eating’ – which helps to destroy bacteria and viruses after infection. When it works, this process counteracts neurodegenerative conditions such as dementia and Huntington’s Disease, by getting rid of unwanted proteins and their resultant harm to cells. But when autophagy fails or defects occur, it can give rise to such […]

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Blood cancer’s Achilles’ heel opens door for new treatments

New findings about a fatal form of blood cancer could aid the development of new drugs with significantly less harmful side effects than existing chemotherapy. The discovery could lead to novel treatments that efficiently eliminate blood cancer cells in acute myeloid leukaemia (AML), without harming healthy blood cells. Researchers have discovered how a protein in the body plays a key […]

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Analyzing colon cancer proteins and genes uncovers new potential treatments

Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible new therapeutic strategies. This multidisciplinary and multi-institutional study led by researchers at Baylor College of Medicine and published in the journal Cell, strongly […]

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New CRISPR tool executes multiple edits simultaneously, leading to unique partnership to deliver cancer treatments

Scientists at Christiana Care Health System’s Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal. The tool can rapidly reproduce, in a human DNA sample, the unique […]

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