New study advances treatment options for PTSD

Stephen Maren, University Distinguished Professor in the Department of Psychological & Brain Sciences, recently published significant research on the psychological and neural basis of Post-Traumatic Stress Disorder (PTSD). Published in Proceedings of the National Academy of Sciences of the United States of America (PNAS), one of the most-cited scientific journals in the world, the study looked at the areas of the […]

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Preeclampsia treatment for mothers also benefits offspring

An estimated six to 15 million people in the U.S. are children born of a pregnancy complicated by preeclampsia. New research performed in rats reveals that treating preeclampsia with sildenafil citrate (Viagra) may help protect the cardiovascular health of the offspring. Preeclampsia occurs when women with otherwise normal blood pressure experience elevated blood pressure during pregnancy. Children of women with […]

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Computational model of a human kinase may provide insights for cancer treatment

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers. The initiation and progression of cancer cells occur when molecular signals involved in cellular proliferation go awry. MEK1 plays an essential role in signaling within both healthy and cancer cells. While much is known about the key […]

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New therapy targets painful side effect of cancer treatment

When Cellix Bio, a drug design firm, approached Dr. Rajesh Lalla to discuss ideas and their patented compounds for a better way to treat oral mucositis, he had no doubt he wanted to be involved. As a professor of dental medicine at UConn Health, Lalla had treated countless patients suffering from this common side effect of cancer treatment. Unfortunately, he […]

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Reducing B cells with CAR T cells is effective treatment of experimental lupus

Depleting the number of harmful B cells with a novel immunotherapy that employs modified T cells may offer an effective strategy to treat lupus, according to a new study funded by the Lupus Research Alliance. These findings offer a renewed optimism for the elimination of B cells to provide a therapeutic option in lupus and pave the way for clinical […]

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Zac Oliver’s mother describes the toll his cancer treatment has taken

Diary of Britain’s bravest boy: He’s the four-year-old whose fight with cancer moved you to help save his life. Now, Zac Oliver’s mother describes the toll his treatment has taken — and the joyful hope that the worst is over… Zac Oliver, 4, was diagnosed with an incredibly rare form of leukaemia in 2018 The youngster was given a less […]

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Multifocal breast cancer: Definition, staging, prognosis, and treatment

There are many types of breast cancer. The type and characteristics, including the number of tumors and where they are, can affect a person’s treatment and long-term outlook. This article covers information about multifocal breast cancer, including how doctors diagnose and treat the condition, its prognosis, and recurrence rates. What is multifocal breast cancer? A person who has received a […]

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Antihypertension drug losartan may improve treatment of ovarian cancer

A new study from a Massachusetts General Hospital (MGH) research team has found that the hypertension drug losartan, which targets the angiotensin signaling pathway, may improve the effectiveness of chemotherapy agents used to treat ovarian cancer. Previous research from the same team identified a similar effect for losartan in animal models of breast and pancreatic cancer, leading to a phase […]

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Crystal wand could magic away a faulty heartbeat for million Britons

Crystal wand could magic away a faulty heartbeat: New device ‘will revolutionise’ atrial fibrillation treatment for one million Britons AcQMap could revolutionise treatment for million Britons with atrial fibrillation The device uses soundwaves to detect precisely where faulty heart beats are  Device consists of catheter, with a basket at its tip, that expands inside the heart  AcQMAP is only available in UK […]

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