New yardstick offers diagnostic and treatment guidance for idiopathic anaphylaxis: Guidelines on next steps when there is no clear cause of severe reactions

Many people in danger of the severe allergic reaction known as anaphylaxis understand exactly what they need to avoid to stay safe. For some it’s an allergy to food, for others it can be insect stings, medications, hormones or even physical factors like exercise. But according to the new “Idiopathic Anaphylaxis Yardstick,” there are people for whom diagnosis and treatment […]

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Genetic discovery linked to rare eye disease

John A. Moran Eye Center physician-researcher Paul S. Bernstein, MD, PhD, and his patients at the University of Utah played a key role in the recent discovery of the first genetic cause for a rare eye disease. Macular telangiectasia type 2 (MacTel) affects about one in 5,000 people, causing a gradual loss of central vision, typically after age 40. As […]

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Patients taking nivolumab experience five-fold increase in overall survival compared to chemotherapy: Five-year outcomes from the randomized, phase 3 trials checkmate 017/057: nivolumab vs. docetaxel in previously treated NSCLC

Pooled data on two clinical trials demonstrate patients taking nivolumab realized a greater than five-fold increase in five-year overall survival rate compared with the chemotherapy docetaxel. The presentation was made today by Dr. Scott Gettinger of Yale Comprehensive Cancer Center, New Haven, Conn., at the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study […]

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Survey shows many primary care doctors are unprepared to help patients avoid diabetes

Which of these is not a risk factor for prediabetes? A) Overweight B) Age 45 or older C) Being white D) Exercise less than three times per week The correct response is C — the actual risk factor being African American, Latino, Native American or Asian American. If you didn’t get it right, don’t feel badly. Chances are your doctor […]

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For patients with diabetes, ticagrelor reduced heart attacks, strokes: Benefits particularly favorable in patients with prior coronary artery stenting; patients also experienced increased risk of bleeding

In late-breaking clinical trial results presented in a Hot Line Session today at the European Society of Cardiology Congress 2019, investigators from Brigham and Women’s Hospital and Greater Paris University Hospitals — AP-HP/Université de Paris presented the results from The Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study (THEMIS), a clinical trial sponsored by AstraZeneca that […]

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Seeing it both ways: Visual perspective in memory: Recalling memories from first- or third-person can change how well you remember them over time

Think of a memory from your childhood. Are you seeing the memory through your own eyes, or can you see yourself, while viewing that child as if you were an observer? “If memory was simply an exact recollection of our experiences, one would think that we would recall our early memories from the first-person perspective,” said Peggy St Jacques, assistant […]

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Augmented reality glasses may help people with low vision better navigate their environment: Glasses enhance mobility and function in patients who have difficulty with peripheral vision or seeing in low light

Nearly one in 30 Americans over the age of 40 experience low vision — significant visual impairment that can’t be corrected with glasses, contact lenses, medication or surgery. In a new study of patients with retinitis pigmentosa, an inherited degenerative eye disease that results in poor vision, Keck School of Medicine of USC researchers found that adapted augmented reality (AR) […]

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Anxiety, depression linked to more opioid use after surgery

Surgeons wielding their life-saving scalpels, laparoscopic tools, or other implements to repair or remove what ails their patients understand all too well that pain is an unavoidable part of the healing process. Yet the current opioid crisis has made the standard prescribing practices for these highly effective analgesics fraught with risk. New research from Michigan Medicine could help clinicians mitigate […]

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Tiny lensless endoscope captures 3D images of objects smaller than a cell: Self-calibrating technology opens new opportunities for medicine and research

Researchers have developed a new self-calibrating endoscope that produces 3D images of objects smaller than a single cell. Without a lens or any optical, electrical or mechanical components, the tip of the endoscope measures just 200 microns across, about the width of a few human hairs twisted together. As a minimally invasive tool for imaging features inside living tissues, the […]

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Blood pressure recording over 24 hours is the best predictor of heart and vascular disease

High blood pressure is the most important treatable risk factor for diseases of the heart and the arterial system. Blood pressure recorded over 24 hours predicts these complications more accurately than blood pressure measured on a single occasion. That is the conclusion of an international study coordinated by Professors Jan A. Staessen and Zhen-Yu Zhang of KU Leuven in Belgium. […]

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