Peripheral nervous system events not common in lupus

(HealthDay)—Peripheral nervous system (PNS) disease is a component of systemic lupus erythematosus (SLE) disease activity and has a significant negative impact on health-related quality of life, according to a study published in the January issue of Arthritis & Rheumatology. John G. Hanly, M.D., from the Queen Elizabeth II Health Sciences Center and Dalhousie University in Halifax, Nova Scotia, Canada, and […]

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New classification system for tumors can guide diagnosis and treatment options for cancer

Based on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumours. Clinicians can use genome sequencing to assign their patients’ tumours to one of sixteen groups in the new classification system, ten of which provide important information for the diagnosis and treatment of the disease, like whether an individual will respond […]

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New model explains how our immune system sometimes helps cancer spread

Mathematicians at the University of Alberta have developed a model that explains how the immune system interacts with cancer—and in some cases, may help cancer spread to other areas of the body. “Past research has shown that sometimes, the immune system has the opposite effect of what we might expect,” said Thomas Hillen, a mathematical biologist at the U of […]

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Deaths increase under new heart donor system, research team finds

Deaths following heart transplants have increased in the year after a new allocation system was put in place to reduce wait times and prioritize donor organs for the sickest patients. The finding by Dr. Rebecca Cogswell at the University of Minnesota and colleagues is a preliminary look at the effect of the new system for deciding which donor hearts go […]

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Using the immune system as a defence against cancer

Research published today in the British Journal of Cancer has found that a naturally occurring molecule and a component of the immune system that can successfully target and kill cancer cells, can also encourage immunity against cancer resurgence. Several teams led by Professor Livio Mallucci from King’s College London discovered that β-galactoside-binding protein (βGBP), a naturally occurring molecule produced by […]

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Endocannabinoid system may be involved in human testis physiology

The endocannabinoid system (ECS) may be directly involved in the regulation of the physiology of the human testis, including the development of sperm cells, according to a study in tissue samples from 15 patients published in Scientific Reports. The ECS is a signalling system consisting of endocannabinoids—a type of neurotransmitter—their associated receptors, enzymes and proteins. In humans, the ECS has […]

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Bacteria injections help the immune system fight cancer

Cancers evade destruction by convincing some immune cells to suppress others. But a surprising interlocutor can persuade the suppressors to defect, and the destroyers to redouble. A review published in Frontiers in Oncology explains how bacteria can rally immune cells to attack tumors, via ancient lines of chemical communication with our immune system. Decoding these molecular signals is key to […]

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The type of fast you do could matter to your immune system

Those interested in fasting, to boost their health or lose a little belly fat, are not starved for choice. As the trend has grown in popularity, so too have the number of ways in which we can do it. There’s the 16:8, the 5:2, the fast 800, alternate-day fasting, fast "mimicking" and the eat-stop-eat 24-hour fast. But not all types […]

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