Study suggests way to prevent rare pulmonary disease

Research by Vanderbilt scientists suggests that it may be possible to prevent or even reverse pulmonary arterial hypertension (PAH), a rare, progressive disease characterized by narrowing of and high blood pressure in the small arteries of the lungs. A key player in PAH is the proangiogenic cell (PAC), a cell produced by the bone marrow that normally promotes the growth […]

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Study shows immunotherapy drug helps patients with metastatic melanoma

When melanoma turns metastatic, it spreads to the brain in more than 40% of patients. A study by Yale Cancer Center researchers published today in the Journal of Clinical Oncology (JCO) shows a checkpoint inhibitor immunotherapy drug has meaningful benefit for these patients. The study is one of the first clinical trials aimed at treating the brain metastases with this […]

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Autism is associated with zinc deficiency in early development—now a study links the two

The emergence of autism in children has not only been linked to genes encoding synaptic proteins—among others—but also environmental insults such as zinc deficiency. Although it is unclear whether zinc deficiency contributes to autism, scientists have now defined in detail a possible mechanistic link. Their research shows how zinc shapes the connections or ‘synapses’ between brain cells that form during […]

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Lax state gun laws linked to more child, teen gun deaths, study finds

Compared with U.S. states with the strictest gun control legislation, gun deaths among children and teenagers are twice as common in states with the most lax gun laws, a study from the Stanford University School of Medicine has found. In addition, states with laws that restrict children’s access to guns have lower rates of firearm-related suicides among youth, even after […]

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Complete Results from First Study in Ongoing Phase 3 Program for Tanezumab Demonstrated Significant Improvement in Pain and Function in Osteoarthritis Patients

NEW YORK & INDIANAPOLIS–(BUSINESS WIRE October 23, 2018 )–Pfizer Inc. (NYSE:PFE) and Eli Lilly and Company (NYSE:LLY) today announced complete results from a Phase 3 study evaluating the efficacy and safety of subcutaneous administration of tanezumab, an investigational humanized monoclonal antibody, in patients with osteoarthritis (OA) pain treated for 16 weeks. The study met all three co-primary efficacy endpoints, demonstrating […]

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Novel technique can potentially improve success of ovarian cancer treatment, study reveals

Novel Technique Can Potentially Improve Success of Ovarian Cancer Treatment, Study Reveals Instead of destroying a tumour’s blood supply, a first-ever University of Guelph study has proven that opening up the vessels is potentially more effective when it comes to fighting ovarian cancer. This is because open vessels provide a clear pathway for treatment to attack the tumour. “There hasn’t […]

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