European guidelines on lipid control advocate ‘lower is better’ for cholesterol levels

Low-density lipoprotein (LDL) cholesterol levels should be lowered as much as possible to prevent cardiovascular disease, especially in high and very high risk patients. That’s one of the main messages of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) Guidelines on dyslipidaemias published online today in European Heart Journal and on the ESC website. Cardiovascular disease (CVD) […]

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For patients with diabetes, ticagrelor reduced heart attacks, strokes: Benefits particularly favorable in patients with prior coronary artery stenting; patients also experienced increased risk of bleeding

In late-breaking clinical trial results presented in a Hot Line Session today at the European Society of Cardiology Congress 2019, investigators from Brigham and Women’s Hospital and Greater Paris University Hospitals — AP-HP/Université de Paris presented the results from The Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study (THEMIS), a clinical trial sponsored by AstraZeneca that […]

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Childhood cholesterol, blood pressure, weight and smoking predict adult heart disease

The first reliable evidence of a link between major cardiovascular risk factors in children — serum cholesterol, blood pressure, body mass index (BMI), and smoking — with cardiovascular disease in adults is presented today at ESC Congress 2019 together with the World Congress of Cardiology. The study highlights the need to lay the foundations for heart health early in life. […]

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Blood pressure recording over 24 hours is the best predictor of heart and vascular disease

High blood pressure is the most important treatable risk factor for diseases of the heart and the arterial system. Blood pressure recorded over 24 hours predicts these complications more accurately than blood pressure measured on a single occasion. That is the conclusion of an international study coordinated by Professors Jan A. Staessen and Zhen-Yu Zhang of KU Leuven in Belgium. […]

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Birthweight, height together provide insight into future heart health

It’s the proportionately of a newborn — a measure that includes both birthweight and length — that may best tell doctors whether a child is born with an increased risk for heart problems later in life, investigators report. Birthweight, while important, tells only part of the story of fetal growth, while the additional consideration of length, gives a more complete […]

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Exploring genetic ‘dark matter,’ researchers gain new insights into autism and stroke

With its elegant double helix and voluminous genetic script, DNA has become the of darling of nucleic acids. Yet, it is not all powerful. In order for DNA to realize its potential — for genes to become proteins — it must first be transcribed into RNA, a delicate molecule that requires intense care and guidance. “Gene expression is a lot […]

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Physical activity in preschool years can affect future heart health

Physical activity in early childhood may have an impact on cardiovascular health later in life, according to new research from McMaster University, where scientists followed the activity levels of hundreds of preschoolers over a period of years. They found that physical activity in children as young as three years old benefits blood vessel health, cardiovascular fitness and is key to […]

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A gut check for heart failure patients

Heart failure patients who consume more dietary fibre tend to have healthier gut bacteria, which is associated with reduced risk of death or need of a heart transplant. The fibre study was presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology (ESC). “Our gut microbiota is composed of trillions of microorganisms that have the […]

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Defects in heart valve cilia during fetal development cause mitral valve prolapse

Genetic variation in heart valve cells of the developing fetus create the blueprint for the later development of mitral valve prolapse, according to the cover story of today’s Science Translational Medicine. The mutations cause defects in antenna-like cellular structures called primary cilia that previously had no known function in the heart valves. These findings were made possible by an international […]

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New approach uses magnetic beads to treat preeclampsia

Preliminary laboratory tests show that functionalized magnetic beads successfully reduced blood levels of a harmful molecule that is elevated during preeclampsia, according to new research in the American Heart Association’s journal Hypertension. Preeclampsia is a complication of pregnancy characterized by hypertension and kidney dysfunction that affects an estimated 6% — 8% of women in the U.S. who give birth each […]

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