Scientists eager to explain brain rhythm boost’s broad impact in Alzheimer’s models

The sweeping extent to which increasing 40Hz “gamma” rhythm power in the brain can affect the pathology and symptoms of Alzheimer’s disease in mouse models has been surprising, even to the MIT neuroscientists who’ve pioneered the idea. So surprising, in fact, they can’t yet explain why it happens. In three papers, including two this year in Cell and Neuron, they’ve […]

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Scientists reliably predict people’s age by measuring proteins in blood

The carnival worker who tries to guess your age relies on aspects of your appearance, such as your posture and whether any wrinkles emanate from the corners of your eyes and lips. If the carny’s guess is more than a few years off, you win a stuffed koala. But a team of Stanford University School of Medicine scientists doesn’t need […]

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Scientists slam Chinese CRISPR babies research after manuscript released

The gene editing performed on Chinese twins last year meant to immunize them against HIV may have failed in its purpose and created unintended mutations, scientists said Tuesday after the original research was made public for the first time. Excerpts from the manuscript were released by the MIT Technology Review for the purpose of showing how Chinese biophysicist He Jiankui […]

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Scientists crack rabies virus weaponry

Researchers have found a way to stop the rabies virus shutting down the body’s immune defence against it. In doing so they have solved a key scientific puzzle and have laid the foundation for the development of new anti-rabies vaccines. Rabies kills an estimated 60,000 people a year, most of them in developing countries, overwhelmingly through dog bites. Monash University […]

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Scientists discover a new strain of HIV for the first time since 2000

Scientists find new strain of HIV for the first time since 2000 – and they say the discovery is a step toward ending the pandemic by including it in testing, treatment and potential vaccines Scientists at Abbott Labs have confirmed that a strain of HIV that infected three people in the Democratic Republic of Congo is a new variety of […]

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Scientists reverse fibrosis in preclinical studies

In cell and mouse models, Mayo Clinic researchers and collaborators have identified a way to slow and reverse the process of uncontrolled internal scarring, called fibrosis. This disease process has few effective therapies, no cure and can be fatal when it occurs in organs such as the liver (cirrhosis) or lungs (pulmonary fibrosis). The findings appear Wednesday, Oct. 30, in […]

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Video: Scientists visualize pain’s pathway

The lab of Stephen Waxman, Bridget M. Flaherty Professor of Neurology and of Neuroscience, has identified the key role of sodium channels arrayed on nerve cells in experience of pain. In a new paper published in Science Advances, the Yale team led by postdoctoral associate Liz Akin and senior research scientist Sulayman Dib-Hajj was able to visualize at the level […]

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Scientists predict the areas of the brain to stimulate transitions between different brain states

A fundamental question in neuroscience is how to force the transition from one brain state to another, for example, from sleep to wakefulness, or in the face of brain pathologies, such as psychiatric diseases and impaired consciousness. As Gustavo Deco and Josephine Cruzat point out: “it is feasible to force the transition from one brain state to another by means […]

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