Tweaked CRISPR in neurons gives scientists new power to probe brain diseases

A team of scientists at UC San Francisco and the National Institutes of Health have achieved another CRISPR first, one which may fundamentally alter the way scientists study brain diseases. In a paper published August 15 in the journal Neuron, the researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity […]

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Scientists pinpoint new mechanism that impacts HIV infection

A team of scientists led by Texas Biomed’s Assistant Professor Smita Kulkarni, Ph.D. and Mary Carrington, Ph.D., at the Frederick National Laboratory for Cancer Research, published results of a study that pinpointed a long noncoding RNA molecule which influences a key receptor involved in HIV infection and progression of the disease. This newly-identified mechanism could open up a new avenue […]

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Scientists develop a physical biomarker for cornea restoration therapy

Our eyes—the windows to the soul—need constant care, and as we age, they sometimes also need significant repair. The panes of these windows—the corneas—are transparent tissues that have been the focus of some of the oldest and most common transplantation surgeries. Now thanks to researchers in Kyoto, some such transplants may become even safer. The team, led by Kyoto University […]

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Pigs help scientists understand human brain

For the first time, researchers in the University of Georgia’s Regenerative Bioscience Center have used an imaging method normally reserved for humans to analyze brain activity in live agricultural swine models, and they have discovered that pig brains are even better platforms than previously thought for the study of human neurological conditions such as Alzheimer’s and Parkinson’s. One immediate potential […]

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Keeping kids’ minds active may cut obesity risks, scientists suggest

Should brain training be part of a healthy diet? Children’s minds use half their energy – and more mental activity might cut obesity risks, scientists say At five, children’s brain’s use up almost half the energy they get from their diets The glucose from food that we don’t use gets converted into fat  Scientists at Northwestern University and New York […]

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Scientists identify a novel neural circuit mediating visually evoked innate defensive responses

Fear overgeneralization, a condition that limits the ability to discriminate between safety and threat, is an important pathological characteristic of anxiety-related syndromes such as post-traumatic stress disorder (PTSD), generalized anxiety disorder (GAD) and panic disorder. However, unlike traditional conditioned fear, the mechanism of processing innate fear is largely unknown. Prof. Wang Liping and his colleagues Zhou Zheng and Liu Xuemei […]

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Scientists discover complex connections between social dynamics and diseases

Large gatherings—from music festivals to religious pilgrimages to sporting events—have long been known to increase risks of infectious disease outbreaks. Now results from an NSF-funded study led by UC Berkeley researchers associate even small-scale community gatherings with increased transmission of diarrheal diseases. The results are published in the American Journal of Epidemiology. Gatherings at events can create environmental and social […]

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Scientists define the role for a rare, influential set of bone marrow cells

Researchers have defined the roles of various cells in the bone marrow that are thought to control the fate of the nearly half million blood cells that develop there each day. Scientists at NYU School of Medicine behind the new work say little had been known about the fraction of cells examined in the study, the “microenvironment” that makes up […]

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Scientists find first evidence for necessary role of the human hippocampus in planning

A team of scientists reports finding the first evidence that the human hippocampus is necessary for future planning. Its findings, published in the journal Neuron, link its long-established role in memory with our ability to use our knowledge to map out the future effects of our actions. The results have implications for the way we think about afflictions that affect […]

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