Promising treatment for an incurable, deadly kidney disease

A potential treatment for polycystic kidney disease — a genetic disorder that causes the kidneys to swell with multiple cysts and can eventually lead to organ failure — has shown promising results in animal testing. A study describing the drug’s development and testing appears today in Nature Communications. The study shows an approximately 50 percent reduction in kidney size in […]

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Mystery solved about the machines that move your genes

Fleets of microscopic machines toil away in your cells, carrying out critical biological tasks and keeping you alive. By combining theory and experiment, researchers have discovered the surprising way one of these machines, called the spindle, avoids slowdowns: congestion. The spindle divides chromosomes in half during cell division, ensuring that both offspring cells contain a full set of genetic material. […]

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Experiments with roundworms suggest alternatives for the treatment of schizophrenia: Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia.

A group of Brazilian scientists have long conducted experiments with roundworms to investigate the role of schizophrenia-linked genes in patients’ response to antipsychotic drugs. The results obtained thus far point to new ways of understanding resistance to certain classes of medication. The studies are conducted by researchers in the Pharmacology Department of the Federal University of São Paulo’s Medical School […]

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Growing evidence: Water as a potential treatment for inherited cause of kidney failure

People with polycystic kidney disease (PKD) could benefit from a moderate increase in water intake, according to new research. A study from The Westmead Institute for Medical Research found that a moderate increase in water intake in rats with PKD led to a long-term reduction in kidney cyst growth and fibrosis. This latest findings add to the growing body of […]

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