Researchers identify targeted therapy that can help children with deadly nerve cancer

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell. Neuroblastoma is one of the most common and aggressive pediatric nervous system tumors and generally has a poor prognosis, particularly when it advances in older […]

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Researchers create new viral vector for improved gene therapy in sickle cell disease

Researchers at the National Institutes of Health have developed a new and improved viral vector—a virus-based vehicle that delivers therapeutic genes—for use in gene therapy for sickle cell disease. In advanced lab tests using animal models, the new vector was up to 10 times more efficient at incorporating corrective genes into bone marrow stem cells than the conventional vectors currently […]

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Researchers study the mechanisms behind learning and long-term memory in the brain

When we first purchase a smart phone, all of our settings and applications are the same. But as time passes, everyone’s phones will change drastically as we adapt them to our own individual needs and preferences. In the same way, our memories and life experiences are loaded into our brains, making one person unique from another. Even the simplest experiences […]

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Researchers move closer to ‘magic’ cancer treatment

Imagine cancer treatment without chemotherapy, radiation or surgery. Just a small aspirin-like pill. Sound like magic? That’s because it kind of is, according to Khaled Barakat, a University of Alberta biophysicist searching for innovative immunotherapies that could help knock out multiple types of cancer simply by empowering the immune system. “We used the word ‘magic’ because the concept is not […]

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Researchers identify new pathway that controls fat formation

In work suggesting new therapeutic targets to fight obesity, UT Southwestern researchers have identified a novel mechanism that regulates the creation of fat in mammals. “Obesity is a global health problem that represents a major risk for several chronic diseases, including Type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular disease, stroke, and cancer,” said Dr. Joshua Mendell, Professor of Molecular […]

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Researchers explore origins of neuron diversity

SMU (Southern Methodist University) researchers have discovered another layer of complexity in gene expression, which could help explain how we’re able to have so many billions of neurons in our brain. Neurons are cells inside the brain and nervous system that are responsible for everything we do, think or feel. They use electrical impulses and chemical signals to send information […]

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Researchers develop novel heart pump to help people with heart failure

Dr. David Adlam, associate professor and interventional cardiologist in the Department of Cardiovascular Sciences and Piyal Samara-Ratna, Mechanical Engineer in the Space Research Centre, have joined forces to combine medical and space research to develop a pump to help people with heart failure. The new left ventricular assist device (LVAD) is an artificial heart pump used as an interim support […]

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Researchers discover how the sun damages our skin

Researchers at Binghamton University, State University of New York have discovered the mechanism through which ultraviolet radiation, given off by the sun, damages our skin. What kind of ultraviolet radiation is the worst for our skin? And how exactly does the sun damage it? Those two questions are at the heart of a new study by Zachary W. Lipsky, a biomedical […]

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Researchers identify barriers to fungal infection diagnosis

There are several barriers that prevent the consistent use of fungal diagnostic preparations to correctly identify cutaneous fungal infections, according to a survey from a team at the George Washington University (GW). The study is published in the Journal of Drugs in Dermatology. Cutaneous fungal infections account for between 3.5 and 6.5 million dermatologist office visits per year. Despite their […]

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Researchers attempt to prove the importance of blood thinners after hospitalization

A study conducted by University of Alabama at Birmingham researchers is attempting to create new guidelines for the use of blood thinners in the weeks following hospitalization. The study, published in the Public Library of Science, found that extending the duration of blood thinners in a patient’s post-discharge period continued to prevent blood clots, including fatal ones. Blood clots in […]

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