Researchers create a better way to transport life-saving vaccines

Researchers at McMaster University have invented a stable, affordable way to store fragile vaccines for weeks at a time at temperatures up to 40C, opening the way for life-saving anti-viral vaccines to reach remote and impoverished regions of the world. The new method combines the active ingredients in existing vaccines with a sugary gel, where they remain viable for eight […]

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Researchers find protein marker for the effectiveness of malaria antibodies

The quantity and quality of antibodies that recognize the end region of the malaria parasite’s CSP protein is a good marker of protection by the RTS,S/AS01E vaccine, according to a study led by the Barcelona Institute for Global Health (ISGlobal) and institutional collaborators. The study, published in Nature Communications, provides valuable information for guiding the design of more effective vaccines. […]

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Researchers find screenings for social determinants of health need to be tailored to clinics

Study of community health centers in Boston finds great deal of variation in practice, as well as in provider and staff opinions about what helps or hinders the process. An estimated 70 percent of the variation in healthcare outcomes is attributable to social determinants——but it is only in recent years that healthcare settings have begun formally looking at these factors […]

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To cheat or not to cheat? Researchers uncover the moral dilemmas of doping

Elite athletes are less likely to take banned substances if they consider the morality of what they are doing, and not just the health consequences of doping, according to a new study led by the University of Birmingham and funded by the World Anti-Doping Agency (WADA). In the study, conducted in UK, Denmark, and Greece, 1,500 athletes were asked to […]

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Researchers find high-risk genes for schizophrenia

Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute (VGI) has identified 104 high-risk genes for schizophrenia. Their discovery, which was reported April 15 in the journal Nature Neuroscience, supports the view that schizophrenia is a developmental disease, one which potentially can […]

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Researchers relate DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are “on” or “off”, and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits. This research evidences that methylation levels in the gene involved in lipid metabolism -Lipoprotein lipase (LPL)- are higher in obese people with a metabolic disease in contrast to healthy people. “Since this […]

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Researchers discover how tumor-killing immune cells attack lymphomas in living mice

In a study that will be published April 1 in the Journal of Experimental Medicine, researchers from the Institut Pasteur and INSERM reveal that chimeric antigen receptor (CAR) T cells can induce tumor regression by directly targeting and killing cancer cells, uncovering new details of how these immune cells work and how their effectiveness could be improved in the treatment […]

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Pediatric health researchers offer insights for RSV vaccine

In healthy adults, RSV, or respiratory syncytial virus, feels like the common cold with a runny nose, chest congestion and cough. However, it is the second leading cause of death in infants. In fact, nearly 40 percent of infants who contract this widespread virus develop severe bronchiolitis or pneumonia, with 1 to 3 percent hospitalized. Each year, there are about […]

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Researchers discover serotonin can regulate gene expression inside neurons

The brain chemical serotonin, a neurotransmitter long known for its role in passing signals between neurons in the brain, can also regulate expression of genes within neurons in an unexpected way, according to research conducted by neuroscientists at the Icahn School of Medicine at Mount Sinai and published on March 13 in the journal Nature. The discovery may help scientists […]

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Researchers discover clues to brain differences between males and females

Researchers at the University of Maryland School of Medicine have discovered a mechanism for how androgens—male sex steroids—sculpt brain development. The research, conducted by Margaret M. McCarthy, Ph.D., who Chairs the Department of Pharmacology, could ultimately help researchers understand behavioral development differences between males and females. The research, published in Neuron, discovered a mechanism for how androgens, male sex steroids, […]

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