Researchers ID risks for second childhood cancers

Chemotherapy and radiation treatments have helped children survive cancer. Now University of Minnesota researchers are trying to find the ideal combinations that prevent the disease from coming back. Comparing outcomes for 22,000 survivors, the researchers found, as expected, that children treated with tumor-killing radiation were at elevated risks of second cancers. But they also discovered that certain chemo drugs increased […]

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Researchers identify a molecular mechanism involved in Huntington’s disease

Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) described a mechanism, the increase of proteinaceous synthesis, which takes part in the degeneration of the type of neurons that are affected in Huntington’s disease, a genetic neurodegenerative disease. These results, published in the journal Brain, could help […]

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Researchers report new insights into Parkinson’s disease-related mortality

By following a group of newly diagnosed patients with Parkinson’s disease (PD) for a decade or more, researchers have been able to identify several factors never before reported that appear to be associated with higher mortality rates in PD patients compared to the general population. As reported in the Journal of Parkinson’s Disease, these factors are early onset of PD, […]

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Researchers partner in vaccine project to tackle major killer of African children

A team of University of Otago researchers is part of a major new international vaccine research project to help tackle devastating Salmonella bloodstream infections which are killing thousands of people in sub-Saharan Africa each year. The recently-launched Vacc-iNTS research project aims to advance the clinical development of an innovative vaccine against invasive non-typhoidal salmonellosis. This is an emerging neglected infectious […]

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Researchers develop noninvasive method to detect early-stage liver disease

A safer and more sensitive contrast dye for MRI tests developed by a team led by Georgia State University researchers may provide the first effective, noninvasive method for detecting and diagnosing early-stage liver diseases, including liver fibrosis. “It’s a revolutionary change for the field as the first robust detection of the early stage of liver fibrosis,” said Jenny Yang, a […]

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Gut instincts: Researchers discover first clues on how gut health influences brain health

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell’s Ithaca campus. Over the last two decades, scientists have observed a clear link between autoimmune disorders and a variety of psychiatric conditions. For example, people with autoimmune disorders such as inflammatory bowel […]

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Researchers identify targeted therapy that can help children with deadly nerve cancer

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell. Neuroblastoma is one of the most common and aggressive pediatric nervous system tumors and generally has a poor prognosis, particularly when it advances in older […]

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Researchers create new viral vector for improved gene therapy in sickle cell disease

Researchers at the National Institutes of Health have developed a new and improved viral vector—a virus-based vehicle that delivers therapeutic genes—for use in gene therapy for sickle cell disease. In advanced lab tests using animal models, the new vector was up to 10 times more efficient at incorporating corrective genes into bone marrow stem cells than the conventional vectors currently […]

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Researchers study the mechanisms behind learning and long-term memory in the brain

When we first purchase a smart phone, all of our settings and applications are the same. But as time passes, everyone’s phones will change drastically as we adapt them to our own individual needs and preferences. In the same way, our memories and life experiences are loaded into our brains, making one person unique from another. Even the simplest experiences […]

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Researchers move closer to ‘magic’ cancer treatment

Imagine cancer treatment without chemotherapy, radiation or surgery. Just a small aspirin-like pill. Sound like magic? That’s because it kind of is, according to Khaled Barakat, a University of Alberta biophysicist searching for innovative immunotherapies that could help knock out multiple types of cancer simply by empowering the immune system. “We used the word ‘magic’ because the concept is not […]

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