Rapamycin may reduce accumulation of a toxic β-thalassemia protein

Rapamycin, a drug widely used to protect organ transplant patients, eased symptoms of β-thalassemia in mice and showed promise for treatment of humans with the inherited disorder, researchers reported. St. Jude Children’s Research Hospital investigators led the study, which appears online today in the journal Science Translational Medicine. Researchers showed that rapamycin worked by activating a protein quality-control pathway—the autophagy […]

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Taking out the protein garbage becomes more difficult as neurons age

Cells dispose of harmful “trash” through autophagy, a normal and necessary process in which aggregated proteins and dysfunctional structures are handled. If any part of this fails, waste builds up inside cells, eventually killing them. According to a new study from the Perelman School of Medicine at the University of Pennsylvania, as cells age, their ability to shed harmful refuse […]

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Promising molecule targets protein to offer hope for people with Parkinson’s

Results from a study published today looking at a molecule targeting clumps of alpha-synuclein, a key protein linked to Parkinson’s, offers hope that it may be possible to slow down or prevent the progression of the condition in humans. Researchers at the University of Cambridge have been able to investigate the effect of a molecule called anle138b, by developing a […]

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Researchers find protein marker for the effectiveness of malaria antibodies

The quantity and quality of antibodies that recognize the end region of the malaria parasite’s CSP protein is a good marker of protection by the RTS,S/AS01E vaccine, according to a study led by the Barcelona Institute for Global Health (ISGlobal) and institutional collaborators. The study, published in Nature Communications, provides valuable information for guiding the design of more effective vaccines. […]

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You Need Vitamin D to Live. How Could This Woman Survive With None in Her Blood?

In 1992, a 33-year-old Lebanese woman had just immigrated to Canada and went to see a doctor. She was hunched over, and had limited mobility in her lower back, neck, shoulders and hips. Her doctor, Raymond Lewkonia at the University of Calgary, diagnosed her with ankylosing spondylitis, a medical condition that causes vertebrae in her spine to fuse, and thought […]

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Diet rich in animal protein is associated with a greater risk of death

A diet rich in animal protein, and meat in particular, is not good for health, a new study from the University of Eastern Finland finds, providing further backing for earlier research evidence. Men who favoured animal protein over plant-based protein in their diet had a greater risk of death in a 20-year follow-up than men whose diet was more balanced […]

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Protein ‘spat out’ by cancer cells promotes tumor growth

Prostate cancer cells change the behaviour of other cells around them, including normal cells, by ‘spitting out’ a protein from their nucleus, new research has found. The tiny pieces of protein are taken up by the other cells, provoking changes that promote tumour growth and—the researchers believe—help the cancer hide from the body’s immune system. The process has been captured […]

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Ocular protein levels may be useful for Alzheimer testing

(HealthDay)—Patients with poor cognitive function have significantly lower levels of Alzheimer disease-related biomarkers in the vitreous humor, according to a study published March 8 in the Journal of Alzheimer’s Disease. Lauren M. Wright, M.D., from the Boston University School of Medicine, and colleagues analyzed vitreous humor samples from 80 eyes of 80 individuals to quantify levels of beta amyloid-β (Aβ40, […]

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Eggs are rather healthy or unhealthy? These nutrients are in the Egg

High-quality Protein, minerals, vitamins: The Egg is stuck numerous healthy nutrients In the past, eggs were considered rather as a health risk and not as a recommended food. But for years now, experts are pointing more and more to the healthy nutrients contained in chicken eggs: high quality Protein, valuable minerals and important vitamins. High cholesterol can be dangerous About […]

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