Endocannabinoid system may be involved in human testis physiology

The endocannabinoid system (ECS) may be directly involved in the regulation of the physiology of the human testis, including the development of sperm cells, according to a study in tissue samples from 15 patients published in Scientific Reports. The ECS is a signalling system consisting of endocannabinoids—a type of neurotransmitter—their associated receptors, enzymes and proteins. In humans, the ECS has […]

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Snout dated: Slow-evolving elephant shark offers new insights into human physiology

The mineralocortoid receptor (MR) regulates water and sodium transport throughout cells and tissues, which is critical for controlling blood pressure and so, not surprisingly, the MR is common to all vertebrate animals. Aldosterone, which is a physiological steroid for land vertebrate MRs, evolved in lungfish (forerunners of land vertebrates), suggesting that the evolution of aldosterone was important in the conquest […]

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