A Rival to Botox Invites Doctors to Party in Cancun, With Fireworks, Confetti and Social Media Posts

Top plastic surgeons and cosmetic dermatologists gathered at the Ritz-Carlton in Cancun one weekend this month to learn about a wrinkle-smoothing injection, Jeuveau, that goes on sale this week. Jeuveau’s manufacturer, Evolus, billed the event as an advisory board meeting. But it also appeared to double as a lavish launch party for Jeuveau, which the company is hoping will compete […]

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Generic Drugmakers Conspired to Inflate Prices Up to 1,000%, State Prosecutors Say

Leading drug companies including Teva, Pfizer, Novartis and Mylan conspired to artificially inflate the prices of generic drugs by as much as 1,000 percent, according to a far-reaching lawsuit filed on Friday by 44 states. The industrywide scheme affected the prices of more than 100 generic drugs, according to the complaint, including lamivudine-zidovudine, which treats H.I.V.; budesonide, an asthma medication; […]

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New computational tool improves gene identification

Like finding a needle in a haystack, identifying genes that are involved in particular diseases can be an arduous and time consuming process. Looking to improve this process, a team led by researchers at Baylor College of Medicine has developed a new bioinformatics tool that analyzes CRISPR pooled screen data and identifies candidates for potentially relevant genes with greater sensitivity […]

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Drug Agency Calls for Strong Warning Labels on Popular Sleep Aids

Federal health regulators announced on Tuesday that they would require manufacturers of sleeping pills such as Ambien and related drugs to post strongly worded warnings in boxes on labels and patient guides. The Food and Drug Administration, in what it called a safety announcement, noted that the drugs’ side effects included risky behaviors, such as sleepwalking and sleep driving, that […]

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‘NarcoLogic’ computer model shows unintended consequences of cocaine interdiction

Efforts to curtail the flow of cocaine into the United States from South America have made drug trafficking operations more widespread and harder to eradicate, according to new research published this week in Proceedings of the National Academy of Sciences. The National Science Foundation supported the study, which included an Oregon State University geographer and was led by Nicholas Magliocca […]

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Transplant Patients Need Anti-Rejection Drugs. Why Won’t Insurers Pay for Some of Them?

The question might seem indelicate. But transplant centers find it is necessary these days to know the answer even before they place a patient on the list for an organ transplant. “How will you pay for the anti-rejection drugs?” These are patients with insurance — they need it to pay for the transplant itself — so it might seem obvious […]

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Exercise helps prevent cartilage damage caused by arthritis

Exercise helps to prevent the degradation of cartilage caused by osteoarthritis, according to a new study from Queen Mary University of London. The researchers show for the first time how mechanical forces experienced by cells in joints during exercise prevent cartilage degradation by suppressing the action of inflammatory molecules which cause osteoarthritis. The study, published in the journal Osteoarthritis and […]

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TB: Promising new drugs for old pathogen Mtb

Tuberculosis (TB), an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective. In the face of this reality, Dennis Wright, professor of medicinal chemistry in the University of Connecticut’s Department of Pharmaceutical Sciences, […]

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Doctors Welcome New Depression Drug, Cautiously

Doctors welcomed federal approval this week of a new, fast-acting nasal spray for depression. But also they expressed concerns about its cost and long-term effects, as well as the logistics of administering it in accordance with safety requirements. The new drug, esketamine, made by Janssen Pharmaceuticals, won approval from the Food and Drug Administration on Tuesday for people who have […]

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