Molecular bodyguards against Parkinson’s disease

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson’s disease. A disturbed relationship to these “bodyguards” leads to cell damage and the formation of Lewy bodies typical for Parkinson’s disease. The findings by researchers from the University of Basel’s Biozentrum have been published in Nature. Parkinson’s disease is one of the most […]

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The pathway to Parkinson’s takes a surprising twist

In neurodegenerative conditions like Parkinson’s disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists have long focused on finding out why these neurons die. Now it turns out, they might not even be dead. Researchers at The Rockefeller University found that affected neurons in Parkinson’s disease can shut down without […]

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Researchers report new insights into Parkinson’s disease-related mortality

By following a group of newly diagnosed patients with Parkinson’s disease (PD) for a decade or more, researchers have been able to identify several factors never before reported that appear to be associated with higher mortality rates in PD patients compared to the general population. As reported in the Journal of Parkinson’s Disease, these factors are early onset of PD, […]

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Exercising at home has a positive effect on Parkinson’s patients

In a large double-blind study, Radboud university medical center researchers show that patients in the early stages of Parkinson’s disease can exercise regularly at home for 6 months. This regular exercise has a positive effect on their motor disability comparable to the effect of conventional Parkinson’s medication. Even though exercise is known to be healthy, many people find it difficult […]

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New guideline on Parkinson’s disease aimed at physicians and people with Parkinson’s

A comprehensive new Canadian guideline provides practical guidance for physicians, allied health professionals, patients and families on managing Parkinson disease, based on the latest evidence. The guideline is published in CMAJ (Canadian Medical Association Journal), accompanied by an easy-to-reference infographic and podcast. Parkinson disease is a debilitating, progressive neurological condition that affects quality of life for patients and their caregivers. […]

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Parkinson’s disease: These mouth difficulties could mean you are at risk

Parkinson’s develops when cells in the brain stop working properly and are lost over time. These brain cells produce a chemical called dopamine. Symptoms start to appear when the brain can’t make enough dopamine to control movement properly. People with Parkinson’s disease commonly experience tremor (shaking), slowness of movement and rigidity (muscle stiffness) – but there are many other symptoms […]

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Smart brain stimulators: Next-gen Parkinson’s disease therapy

Researchers at the University of Houston have found neuro biomarkers for Parkinson’s disease that can help create the next generation of “smart” deep brain stimulators, able to respond to specific needs of Parkinson’s disease patients. Those with the disease often undergo the high-frequency brain stimulation, a well-established therapy for the progressive nervous system disorder that affects movement, but the therapy […]

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Ear stimulation may help manage Parkinson’s symptoms, says study

The stimulation therapy was performed at home using a portable headset produced exclusively for clinical investigations by Scion Neurostim, a US-based device company. A gentle, controlled stimulation of the ear canal may help reduce symptoms of Parkinson’s disease, according to a study. The study, published in the journal Parkinsonism and Related Disorders, showed that twice-daily stimulation for two months was […]

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Parkinson’s disease: The five stages of Parkinson’s disease and how to spot the condition

Parkinson’s disease is characterised by the loss of cells of the brain or spinal cord, which over times leads to dysfunction and disability. It affects predominantly dopamine-producing neutrons in a specific area of the brain. The cause of Parkinson’s remains largely unknown and although there is no cure there are many treatment options including medications and surgery. Stage one The […]

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