Genetic study provides novel insights into the evolution of skin color

Skin colour is one of the most visible and variable traits among humans and scientists have always been curious about how this variation evolved. Now, a study of diverse Latin American populations led by UCL geneticists has identified new genetic variations associated with skin colour. The study, published in the journal Nature Communications, found that the variation of light skin […]

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Researchers design algorithms to improve detection of early cognitive impairment

Researchers at the Pharmacy and Mathematics departments of the CEU UCH University in Valencia have collaborated on the design of two artificial intelligence algorithms that improve the screening of positive cases in the early detection of cognitive impairment in chemists. These algorithms also make it possible to identify the main risk factors of developing some type of dementia in the […]

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Orthodontics no guarantee of long-term oral health

A commonly held belief among the general public is orthodontic treatment will prevent future tooth decay. Research undertaken at the University of Adelaide has found that this is not the case. Published in the journal Community Dentistry and Oral Epidemiology, the study, conducted by Dr. Esma J Dogramaci and co-author Professor David Brennan from the University’s Adelaide Dental School, assessed […]

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Protecting oligodendrocytes may reduce the impact of multiple sclerosis

A small molecule, Sephin1, may be able to significantly delay harm to nerve cells caused by multiple sclerosis, a disabling immune-mediated disease that damages nerve fibers in the brain and spinal cord. These nerve fibers are wrapped in a sheath of fatty tissue called myelin, which acts as a protective blanket, like insulation around an electrical wire. The myelin sheath […]

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Regulation and potential drug targets of tumor-associated Tregs

According to estimates from the World Health Organization (WHO), there will be 18.1 million new cases and 9.6 million cancer deaths worldwide in 2018. Cancer is a serious disease that affects people all over the world. And studies on the treatment of tumors have far-reaching significance. In recent years, tumor immunotherapy has become the fourth-ranking cancer treatment measure in line […]

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Antihypertension drug losartan may improve treatment of ovarian cancer

A new study from a Massachusetts General Hospital (MGH) research team has found that the hypertension drug losartan, which targets the angiotensin signaling pathway, may improve the effectiveness of chemotherapy agents used to treat ovarian cancer. Previous research from the same team identified a similar effect for losartan in animal models of breast and pancreatic cancer, leading to a phase […]

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Medically assisted reproduction does not raise risk of preterm birth and low birth weight

Couples considering medically assisted reproduction (MAR) because they have difficulty conceiving naturally have feared the possibility of preterm birth (less than 37 weeks of pregnancy) and low birth weight (less than 2.5 kilograms). Doctors often warn prospective parents about these risks. It’s a hard decision for couples with an unmet desire for children. Low birth weight children have more respiratory, […]

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Better oral health with new type of glass ceramic

Researchers at Ångström Laboratory at Uppsala University have now developed glass ceramics that are three times stronger than current ones. This paves the way for better dental care where patients benefit from stronger teeth and do not have to visit their dentist as often. Ceramics are inorganic and non-metallic materials that constitute the main group of materials. Examples of ceramics […]

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Making the most of a well-woman checkup

(HealthDay)—Don’t wait until you get sick to see a doctor—wellness visits for women can catch problems before they become serious, as well as make sure you’re taking all the right steps for good health. A well-woman checkup focuses on preventive care. It may include immunizations, screenings to check your blood pressure, cholesterol levels and other health markers, and advice for […]

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Role of PCSK9 inhibitors in high risk patients with dyslipidemia

Familial hypercholesterolemia (FH) is an inherited autosomal dominant disorder which is characterized by substantially increased Low-Density Lipoprotein Cholesterol (LDL-C) levels. Timely reduction of LDL-C is of paramount importance to ameliorate the risk for CV disease as patients with FH have a significantly higher risk for Cardiovascular (CV) events. Pro-protein Convertase Subtilisin/Kexin type 9 (PCSK9) inhibitors have emerged as a very […]

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