Researchers identify targeted therapy that can help children with deadly nerve cancer

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell. Neuroblastoma is one of the most common and aggressive pediatric nervous system tumors and generally has a poor prognosis, particularly when it advances in older […]

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Antibiotic use can increase nerve damage risk

Research from the University of Dundee has shown that a commonly used class of antibiotics may increase a patient’s risk of suffering a serious and potentially permanent form of nerve damage by almost 50 percent. Peripheral neuropathy has long been recognised as a potential side effect of fluoroquinolone antibiotics but it was not known how strong this association was and […]

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Multitasking with perfection: Nerve cell works like 1400 individual cells

CT1 is different. In general, a nerve cell receives input from a number of presynaptic cells, processes the signals, and passes its output to downstream cells. In the cell CT1, however, each of the approximately 1400 cell areas works like a separate neuron. This allows CT1 to access information from all facets of the fly’s complex eye and to contribute […]

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New target could help protect vision following optic nerve trauma

When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report. They have shown for the first time in a mouse model of tough-to-treat optic nerve trauma, that removing the enzyme arginase 2, which increases with injury, decreases neuron death in the retina as well as […]

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Research confirms nerve cells made from skin cells are a valid lab model for studying disease

The incidence of some neurological diseases—especially those related to aging, such as Alzheimer’s and Parkinson’s diseases—is increasing. To better understand these conditions and evaluate potential new treatments, researchers need accurate models that they can study in the lab. Researchers from the Salk Institute, along with collaborators at Stanford University and Baylor College of Medicine, have shown that cells from mice […]

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Elucidation of central mechanisms of salt-induced hypertension through activation of sympathetic nerve activities

Hypertension is a major risk factor for cardiovascular disease worldwide, and approximately 40 percent (1 billion) of adults aged 25 and above have been diagnosed with hypertension (World Health Organization 2013; ref. 1). A positive correlation between salt (NaCl) intake and blood pressure (BP) has long been postulated. A battery of studies has shown that a diet high in salt […]

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