New target could help protect vision following optic nerve trauma

When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report. They have shown for the first time in a mouse model of tough-to-treat optic nerve trauma, that removing the enzyme arginase 2, which increases with injury, decreases neuron death in the retina as well as […]

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Research confirms nerve cells made from skin cells are a valid lab model for studying disease

The incidence of some neurological diseases—especially those related to aging, such as Alzheimer’s and Parkinson’s diseases—is increasing. To better understand these conditions and evaluate potential new treatments, researchers need accurate models that they can study in the lab. Researchers from the Salk Institute, along with collaborators at Stanford University and Baylor College of Medicine, have shown that cells from mice […]

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Elucidation of central mechanisms of salt-induced hypertension through activation of sympathetic nerve activities

Hypertension is a major risk factor for cardiovascular disease worldwide, and approximately 40 percent (1 billion) of adults aged 25 and above have been diagnosed with hypertension (World Health Organization 2013; ref. 1). A positive correlation between salt (NaCl) intake and blood pressure (BP) has long been postulated. A battery of studies has shown that a diet high in salt […]

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