Statins could protect against motor neurone disease

High cholesterol has been found to be a possible risk factor for the development of motor neurone disease (MND), according to a large study of genetic data led in the UK by Queen Mary University of London, in collaboration with the National Institutes of Health in the USA. The results suggest that cholesterol-lowering drugs, such as statins, could be used […]

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Scientists identify new disrupted pathway in motor neurone disease

Researchers at the University of Sheffield have identified a new pathway that is disrupted in motor neurone disease (MND), a discovery which could pave the way for new treatments. The ground breaking findings were discovered by converting skin cells to brain cells called astrocytes, and comparing the energy metabolism of cells taken from MND patients versus healthy controls, using a […]

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Zebrafish help unlock mystery of motor neurone disease

Scientists from the University of Sheffield have successfully created zebrafish that carry the complex genetic change known to cause the most common genetic form of motor neurone disease (MND). The breakthrough will help to accelerate pioneering research and experimental drug trials to tackle the degenerative disease. Until now, research to better understand how the disease occurs and the trial of […]

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