Understanding probiotic yeast

Researchers led by Prof. Johan Thevelein (VIB-KU Leuven Center for Microbiology) have discovered that Saccharomyces boulardii, a yeast with probiotic properties, produces uniquely excessive amounts of acetic acid, the main component of vinegar. They were also able to find the genetic basis for this trait, which allowed them to modify the acetic acid production of the yeast. If this unique […]

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How chikungunya virus may cause chronic joint pain

A new method for permanently marking cells infected with chikungunya virus could reveal how the virus continues to cause joint pain for months to years after the initial infection, according to a study published August 29 in the open-access journal PLOS Pathogens by Deborah Lenschow of Washington University School of Medicine in St. Louis, and colleagues. According to the authors, […]

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Strain of common cold virus could revolutionize treatment of bladder cancer

A strain of the common cold virus has been found to potentially target, infect and destroy cancer cells in patients with bladder cancer, a new study in the medical journal Clinical Cancer Research reports. No trace of the cancer was found in one patient following treatment with the virus. Researchers from the University of Surrey and Royal Surrey County Hospital […]

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Over-fed bacteria make people sick

In a new hypothesis, a CRC 1182 research team suggests that inflammatory diseases are caused by an over-supply of food, and the associated disturbance of the intestine’s natural bacterial colonization. Since the end of the Second World War, along with the growing prosperity and the associated changes in lifestyle, numerous new and civilisation-related disease patterns have developed in today’s industrialised […]

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Drug can reverse hyperactivity induced by parasitic infection

When rodents get infected by Toxoplasma gondii, the single-celled brain parasite that causes toxoplasmosis, they become hyperactive risk-takers. In findings published this week in mBio, researchers show for the first time that it’s possible to reverse that behavioral change. Surprisingly, the study also showed that the restoration of normal behavior resulted from reducing inflammation — and not from reducing the […]

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New microscope captures large groups of neurons in living animals: Fast, detailed imaging across a wide field of view useful for deciphering brain functions

Researchers have developed a microscope specifically for imaging large groups of interacting cells in their natural environments. The instrument provides scientists with a new tool for imaging neurons in living animals and could provide an unprecedented view into how large networks of neurons interact during various behaviors. In Optica, The Optical Society’s journal for high-impact research, researchers from Boston University, […]

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Bacterial immunity and infectious disease

Patients with cystic fibrosis are often infected by pseudomonas aeruginosa, a bacterium that infects the lungs and prevents breathing, often causing death. P. aeruginosa itself can also be infected by viruses, which can affect the clinical outcomes of cystic fibrosis patients. “Just like humans get infected by bacteria, the bacteria get infected by viruses,” said Rachel Whitaker, a professor of […]

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A bacterial protein is found to promote cancer: Research suggests suggests that bacterial infections may contribute to far more cancers than previously thought

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) announced today the discovery that DnaK, a protein of the bacterium mycoplasma, interferes with the mycoplasma-infected cell’s ability to respond to and repair DNA damage, a known origin of cancer. Little or no mycoplasma DnaK DNA sequences were found associated with the tumor, which was […]

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