New microscopes unravel the mysteries of brain organization: Researchers around the world share their stunning images and insights: The open source mesoSPIM Initiative

The secret of capturing exquisite brain images with a new generation of custom-built microscopes is revealed today in Nature Methods. The new microscopes, known as mesoSPIMs, can image the minute detail of brain tissue down to individual neurons that are five times thinner than a human hair, and can uncover the 3D anatomy of entire small organs, faster than ever […]

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Gold nanoparticles shown to be safe and effective treatment for prostate cancer

Biocompatible gold nanoparticles designed to convert near-infrared light to heat have been shown to safely and effectively ablate low- to intermediate-grade tumors within the prostate, according to a study conducted at the Icahn School of Medicine and published in the journal Proceedings of the National Academy of Sciences. This treatment could offer patients a targeted therapy option that would preserve […]

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Augmented reality glasses may help people with low vision better navigate their environment: Glasses enhance mobility and function in patients who have difficulty with peripheral vision or seeing in low light

Nearly one in 30 Americans over the age of 40 experience low vision — significant visual impairment that can’t be corrected with glasses, contact lenses, medication or surgery. In a new study of patients with retinitis pigmentosa, an inherited degenerative eye disease that results in poor vision, Keck School of Medicine of USC researchers found that adapted augmented reality (AR) […]

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Tiny lensless endoscope captures 3D images of objects smaller than a cell: Self-calibrating technology opens new opportunities for medicine and research

Researchers have developed a new self-calibrating endoscope that produces 3D images of objects smaller than a single cell. Without a lens or any optical, electrical or mechanical components, the tip of the endoscope measures just 200 microns across, about the width of a few human hairs twisted together. As a minimally invasive tool for imaging features inside living tissues, the […]

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Ultrasound-assisted optical imaging to replace endoscopy in breakthrough discovery

Carnegie Mellon University’s Assistant Professor of Electrical and Computer Engineering (ECE) Maysam Chamanzar and ECE Ph.D. student Matteo Giuseppe Scopelliti today published research that introduces a novel technique which uses ultrasound to noninvasively take optical images through a turbid medium such as biological tissue to image body’s organs. This new method has the potential to eliminate the need for invasive […]

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Blood flow monitor could save lives: Fibre-optic probe gives continuous cardiac measure

A tiny fibre-optic sensor has the potential to save lives in open heart surgery, and even during surgery on pre-term babies. The new micro-medical device could surpass traditional methods used to monitor blood flow through the aorta during prolonged and often dangerous intensive care and surgical procedures — even in the tiniest of patients. The continuous cardiac flow monitoring probe, […]

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A miniature robot that could check colons for early signs of disease

Engineers have shown it is technically possible to guide a tiny robotic capsule inside the colon to take micro-ultrasound images. Known as a Sonopill, the device could one day replace the need for patients to undergo an endoscopic examination, where a semi-rigid scope is passed into the bowel — an invasive procedure that can be painful. Micro-ultrasound images also have […]

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Microbes on explanted pedicle screws: Possible cause of spinal implant failure

Pedicle screws are often used to secure surgically implanted hardware to the spine in patients with spinal disease or spinal trauma. In some cases, these screws loosen over time, leading to spinal instability and consequent pain. This is a common complication of spine surgery. One reason suggested for pedicle screw loosening is implant-associated infection, but until now there has been […]

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Organ bioprinting gets a breath of fresh air: Bioengineers clear major hurdle on path to 3D printing replacement organs

Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The new innovation allows scientists to create exquisitely entangled vascular networks that mimic the body’s natural passageways for blood, air, lymph and other vital fluids. The research is featured on the cover of this week’s issue of Science. It […]

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Low-dose radiation therapy improves delivery of therapeutic nanoparticles to brain tumors

A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted and immune-system-based therapies against the deadly brain tumor. The team describes how pretreatment with low-dose radiation increased delivery to tumors of nanoparticles carrying small interfering RNA (siRNA) molecules and significantly […]

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