Benzodiazepines may decrease mortality in congestive heart failure

A study published in the current issue of Psychotherapy and Psychosomatics indicates that treatment of anxiety with benzodiazepines may improve survival in congestive heart failure. Depression (in various forms and as various entities) is usually the main focus of research and treatment among psychiatric comorbidities in CVD patients. Anxiety has usually been lumped together with depression as a risk factor […]

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Protecting oligodendrocytes may reduce the impact of multiple sclerosis

A small molecule, Sephin1, may be able to significantly delay harm to nerve cells caused by multiple sclerosis, a disabling immune-mediated disease that damages nerve fibers in the brain and spinal cord. These nerve fibers are wrapped in a sheath of fatty tissue called myelin, which acts as a protective blanket, like insulation around an electrical wire. The myelin sheath […]

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Recalling Positive Memories May Cut Depression Risk for Teens

TUESDAY, Jan. 15, 2019 — Recalling specific positive life experiences may build resilience and help lower vulnerability to depression among adolescents with a history of early-life stress, according to a research letter published online Jan. 14 in Nature Human Behaviour. Adrian Dahl Askelund, from the University of Cambridge in the United Kingdom, and colleagues used path modeling to assess whether […]

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Antihypertension drug losartan may improve treatment of ovarian cancer

A new study from a Massachusetts General Hospital (MGH) research team has found that the hypertension drug losartan, which targets the angiotensin signaling pathway, may improve the effectiveness of chemotherapy agents used to treat ovarian cancer. Previous research from the same team identified a similar effect for losartan in animal models of breast and pancreatic cancer, leading to a phase […]

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Common pain relievers may worsen C. difficile infection

Clostridium difficile, also called C. difficile or C. diff, is a bacterium that causes inflammation of the colon. This health condition commonly affects older adults in hospitals, and it often occurs after the use of antibiotic medications. According to the Centers for Disease Control and Prevention, C. difficile led to almost half a million infections among patients in the United […]

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Drug Repurposing May Provide More Psychiatric Tx Options

FRIDAY, Jan. 11, 2019 — Three classes of drugs hold potential as repurposed agents to treat patients with serious mental illness, according to a study published online Jan. 9 in JAMA Psychiatry. Joseph F. Hayes, Ph.D., from University College London, and colleagues evaluated the repurposing of hydroxylmethyl glutaryl coenzyme A reductase inhibitors (HMG-CoA RIs), L-type calcium channel (LTCC) antagonists, and […]

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Birthweight and early pregnancy body mass index may risk pregnancy complications

Women who were born with a low birthweight are at increased risk of pregnancy complications, according to a new Obesity study. The findings suggest that women who were born small may have been affected by unfavourable intrauterine conditions, and the physiological demands of pregnancy may act as a “second hit” leading to pregnancy complications. In the study of 5,336 women, […]

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Higher average potency cannabis may increase risk for first disorder symptom

Recreational cannabis is legal in 10 states and Washington, D.C., but regulations regarding potency do not exist. The results of a new study, led by an Iowa State University researcher, may prompt states to reconsider. Higher average potency cannabis at first use increases the risk for the first symptom of cannabis use disorder within a year of use, according to […]

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These bacteria may be the key to treating clinical depression

We like to think of ourselves as individuals. But scientists estimate that we share our bodies with 38 trillion organisms that play an integral part in keeping us healthy and making us who we are. They crawl across our skin, cling to our intestines, and generally call our bodies home. Now, a study led by researchers at Northeastern shows that […]

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Study reveals gut microbes may help protect people having a bone marrow transplant

Researchers at Memorial Sloan Kettering Cancer Center (MSK) reported results from a new study that looks at the likelihood of complications for people undergoing bone marrow transplants (BMTs). The observational study found that people with lower gut microbiota diversity before having a transplant appear to be at higher risk for developing complications. These findings further support evidence that the connection […]

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