Scientists discover new breakthrough in cancer hair-loss treatment

Scientists have determined a new way to protect the hair follicle from chemotherapy in an effort to prevent hair loss as a result of cancer treatments. Researchers based at The University of Manchester have discovered a new strategy for how to protect hair follicles from chemotherapy, which could lead to new treatments that prevent chemotherapy-induced hair loss — arguably one […]

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Patients taking nivolumab experience five-fold increase in overall survival compared to chemotherapy: Five-year outcomes from the randomized, phase 3 trials checkmate 017/057: nivolumab vs. docetaxel in previously treated NSCLC

Pooled data on two clinical trials demonstrate patients taking nivolumab realized a greater than five-fold increase in five-year overall survival rate compared with the chemotherapy docetaxel. The presentation was made today by Dr. Scott Gettinger of Yale Comprehensive Cancer Center, New Haven, Conn., at the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study […]

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Possible new treatment strategy for lung cancer: Combination therapy targeting KRAS mutation could provide benefit to nearly a third of lung cancer patients

Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway. This type of mutation makes the cancer more aggressive and difficult to treat. Researchers at Moffitt Cancer Center are […]

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Better tools, better cancer immunotherapy

In the journal Science Immunology, researchers from DTU Health Technology and Jacobs University in Bremen have just published their cutting-edge research demonstrating advancement in detection of a certain type of immune cells, called T cells. Improved detection of T cells have several therapeutic implications. For example, in cancer immunotherapy (a therapeutic approach that engage patients own immune cells) characterization of […]

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Researchers unlock cancer cells’ feeding mechanism, central to tumor growth: The findings could lead to new treatments by blocking tumor growth at its roots

An international team led by researchers from the University of Cincinnati and Japan’s Keio and Hiroshima universities has discovered the energy production mechanism of cancerous cells that drives the growth of the nucleolus and causes tumors to rapidly multiply. The findings, published Aug. 1 in the journal Nature Cell Biology, could lead to the development of new cancer treatments that […]

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Low level exposure to air pollution is harmful, mouse model shows

Air pollution is made up of both gaseous and particulate matter (PM). Each year almost two million people die as a direct result of air pollution with many more experiencing impaired lung function, developing lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). However research, on the effects of low level air pollution, is often overlooked. An international […]

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Evidence a cancer drug may be extended to many more patients

A new molecular mechanism discovered by UT Southwestern researchers indicates that drugs currently used to treat less than 10 percent of breast cancer patients could have broader effectiveness in treating all cancers where the drugs are used, including ovarian and prostate cancers. The new study also revealed a potential biomarker indicating when these drugs, called PARP inhibitors, can be unleashed […]

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New insight into microRNA function can give gene therapy a boost

Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei. Previously, microRNAs were mainly thought to be found in cytoplasm. The scientists also discovered that microRNA concentrations in cell nuclei change as a result of hypoxia. The findings strongly suggest […]

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Strain of common cold virus could revolutionize treatment of bladder cancer

A strain of the common cold virus has been found to potentially target, infect and destroy cancer cells in patients with bladder cancer, a new study in the medical journal Clinical Cancer Research reports. No trace of the cancer was found in one patient following treatment with the virus. Researchers from the University of Surrey and Royal Surrey County Hospital […]

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Obese people outnumber smokers two to one

New figures from Cancer Research UK show that people who are obese now outnumber people who smoke two to one in the UK*, and excess weight causes more cases of certain cancers than smoking, as the charity urges Government action to tackle obesity. Almost a third of UK adults are obese** and, while smoking is still the nation’s biggest preventable […]

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