3-D model of human liver for better diagnosis

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3-D structural changes. Researchers at the Max […]

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Study finds new option for liver transplant patients

A drug commonly used to treat both asthma and inflammatory bowel disease, budesonide, may also be useful as an anti-organ rejection medication for liver transplant patients leading to fewer serious side effects than the most commonly used therapy, according to a University of Cincinnati researcher. Dr. Khurram Bari, an associate professor in the UC Division of Digestive Diseases, explains the […]

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New research suggests proton radiation can benefit pts with challenging liver tumors

Two new studies support and inform the use of proton radiation therapy to treat patients with hepatocellular carcinoma (HCC), a common but often fatal type of liver cancer for which there are limited treatment options. One study (Sanford et al.) suggests that proton radiation, compared to traditional photon radiation, can extend overall survival with reduced toxicity. A second study (Hsieh […]

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Researchers develop noninvasive method to detect early-stage liver disease

A safer and more sensitive contrast dye for MRI tests developed by a team led by Georgia State University researchers may provide the first effective, noninvasive method for detecting and diagnosing early-stage liver diseases, including liver fibrosis. “It’s a revolutionary change for the field as the first robust detection of the early stage of liver fibrosis,” said Jenny Yang, a […]

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Cell family trees tracked to discover their role in tissue scarring and liver disease

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions. The research by academics from the Universities of Edinburgh and Bristol and funded by the Wellcome Trust and Medical Research Council, is published today [Tuesday 15 October] in Nature Communications. The distinguishing feature of these families—whether […]

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Always Tired? The liver might be sick!

Fatigue and lack of concentration after the holidays: signs of liver disease The Easter holidays are coming up. Anyone who travels in the distance, you can also bring serious disease with home. If you feel unusually tired and listless, you should consult a doctor. Liver disease can be cause. Lack of concentration and lack of drive are symptoms for Hepatitis […]

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Improved Outcomes Seen With Liver Grafts From Older Donors

WEDNESDAY, Feb. 13, 2019 — From 2003 to 2016, liver graft loss and mortality improved among recipients of liver grafts from older donors, according to a study published online Feb. 13 in JAMA Surgery. Christine E. Haugen, M.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues conducted a prospective cohort study involving 4,127 liver grafts from […]

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MRI effective for monitoring liver fat in obese patients

MRI provides a safe, noninvasive way to monitor liver fat levels in people who undergo weight loss treatments for obesity, according to a new study published in the journal Radiology. Obesity is a major U.S. public health issue, with more than two-thirds of American adults considered overweight or obese. Non-alcoholic fatty liver disease is common in obese patients. The condition […]

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Risk factors identified for late recurrence of liver cancer

(HealthDay)—Late recurrence after hepatocellular carcinoma (HCC) resection is associated with sex, cirrhosis, and several aggressive tumor characteristics of the initial HCC, according to a study recently published in JAMA Surgery. Xin-Fei Xu, M.D., from Second Military Medical University in Shanghai, and colleagues examined risk factors, patterns, and outcomes of late recurrence (more than two years) after curative liver resection for […]

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Colder, darker climates increase alcohol consumption and liver disease

Where you live could influence how much you drink. According to new research from the University of Pittsburgh Division of Gastroenterology, people living in colder regions with less sunlight drink more alcohol than their warm-weather counterparts. The study, recently published online in Hepatology, found that as temperature and sunlight hours dropped, alcohol consumption increased. Climate factors also were tied to […]

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