Surprise finding about HIV reservoir could lead to better therapies

Antiretroviral therapy (ART) can suppress HIV to the point where the virus is nearly undetectable, and people on medication can live many years. But therapy cannot completely eradicate the virus; it persists in reservoirs inside immune cells, a phenomenon called “latency.” This latent reservoir forms even when a person begins therapy very early after infection, but the dynamics of the […]

Read more

FitBits do NOT lead to weight loss, study finds

FitBits do NOT lead to weight loss: Study finds little evidence that your wearable is much more than a fancy bracelet Researchers at the University of Florida analyzed 6 studies on 1,615 people They found no users had any meaningful drop in cholesterol or blood pressure Only one cohort recorded noteworthy weight loss  Don’t bother investing in an Apple Watch if […]

Read more

Innate immune responses to high-fat diets lead to obesity

Why is eating a high fat diet a recipe for obesity? According to a new study from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan, the answer involves the activity of a specific type of immune cell that lives in the small intestine. Published in the journal Cell Reports, a series of experiments shows that without group-2 innate […]

Read more

Antidepressants can lead to reductions in behavioral and neural responses to pain empathy

Depression is a disorder that often comes along with strong impairments of social functioning. Until recently, researchers assumed that acute episodes of depression also impair empathy, an essential skill for successful social interactions and understanding others. However, previous research had been mostly carried out in groups of patients who were on antidepressant medication. Novel insights of an interdisciplinary collaboration involving […]

Read more

New discovery in how mammals sense the cold could lead to new pain relief drugs

Researchers at UCL have shown for the first time that mammals detect different intensities of cold using distinct sensory neuron systems, a finding which could lead to the development of new drugs to treat cold pain. The study on mice, published in Proceedings of the National Academy of Sciences, set out to understand more about the two known sensory neuron […]

Read more

Sunscreen use could lead to better blood vessel health

A new study suggests that sunscreen protects the skin’s blood vessel function from harmful ultraviolet radiation (UVR) exposure by protecting dilation of the blood vessels. Perspiration on the skin may also provide protection to the skin’s blood vessels from sun damage. The findings will be presented today at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2019 in […]

Read more

Self-destruction system in TB bacteria may lead to ‘perfect drug’

In the United States, more than 9,000 cases of tuberculosis (TB) occurred in 2017. Though the U.S. has one of the lowest TB rates worldwide, the disease remains one of the top 10 leading causes of death around the globe. In fact, the World Health Organization (WHO) estimate that approximately 10 million people had TB in 2017, and that 1.6 […]

Read more

Targeting chemical signals between the gut and brain could lead to new treatment for obesity

New research published in The Journal of Physiology has shed light on how to disrupt chemical signals that affect how much someone eats, which could lead to a method for helping manage obesity. Obesity is one of today’s most prevalent public health concerns. In the UK it affects around 1 in every 4 adults and around 1 in every 5 […]

Read more