Targeting a blood stem cell subset shows lasting, therapeutically relevant gene editing

In a paper published in the July 31 issue of Science Translational Medicine, researchers at Fred Hutchinson Cancer Research Center used CRISPR-Cas9 to edit long-lived blood stem cells to reverse the clinical symptoms observed with several blood disorders, including sickle cell disease and beta-thalassemia. It’s the first time that scientists have specifically edited the genetic makeup of a specialized subset […]

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General anesthesia is unlikely to have lasting effects on the developing brains of young children: study

A single hour of general anaesthesia in early infancy—longer than is necessary to perform the most common types of minor surgeries in childhood—does not result in measurable neurodevelopmental or behavioural problems up to the age of 5 years, according to the first randomised trial of its kind involving 722 infants in seven countries, published in The Lancet. The trial provides […]

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