Mini-kidneys grown from stem cells provide new insights into kidney disease and potential therapies

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown ‘miniature kidneys’ in the laboratory that could be used to better understand how kidney diseases develop in individual patients. The mini kidneys, known as kidney organoids, were grown outside the body from skin cells derived from a single patient who has polycystic kidney disease, one […]

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One-fifth of US surgeons still overusing riskier procedure to create kidney dialysis access

Long-term hemodialysis is a lifesaver for approximately half a million patients in the United States with kidney failure (also known as end-stage renal disease, or ESRD) who are either waiting on or unsuitable for a kidney transplant. But before the external machinery can take over the function of the kidneys—filtering and cleansing wastes from the blood—a minor surgical procedure is […]

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Chronic kidney disease of undetermined causes described originally in Central America and Sri Lanka

Chronic kidney disease of undetermined causes (CKDu), initially reported among agricultural communities in Central America and Sri Lanka, is also present in India, particularly in Southern rural areas, and could be common in other tropical and subtropical rural settings. These are the main conclusions of a new study published in BMJ Open. CDKu is considered an epidemic in Central America […]

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Study may explain why immunotherapy not effective for some patients with metastatic melanoma and kidney cancer

White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. Study results will be presented April 2 at the AACR Annual Meeting 2019 in Atlanta. The study, led by Jennifer Wargo, […]

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Girl writes letter to Santa Claus asking for a kidney for her brother

Girl writes heart-wrenching letter to Santa Claus asking for a new kidney for her big brother – and posts it in a department store mailbox The letter is believed to have been written on Friday, November 23, at a Lowe’s department store in Franklin, North Carolina Written in green, blue and purple crayon, the letter asks Santa for a kidney transplant […]

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Research review underscores progress in treating kidney cancer, importance of close patient monitoring

With the swift introduction of approved immunotherapy approaches into the treatment landscape for many cancers, medical professionals across many care-delivery settings and specialties are tasked with the need to follow and understand a set of treatment standards that are changing rapidly. The treatment of renal cell carcinoma (RCC), or kidney cancer, has been one of the fields most dramatically affected […]

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Brain, muscle cells found lurking in kidney organoids grown in lab

Scientists hoping to develop better treatments for kidney disease have turned their attention to growing clusters of kidney cells in the lab. One day, so-called organoids—grown from human stem cells—may help repair damaged kidneys in people or be used to test drugs developed to fight kidney disease. But new research from Washington University School of Medicine in St. Louis has […]

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