Athletes at a higher risk for ACL injury after return to sport

Young athletes who do not achieve a 90 percent score on a battery of tests that measure fitness to return to athletic competition, including quadricep strength, are at increased risk for a second knee injury, according to research presented at the Annual Meeting of the American Orthopedic Society of Sports Medicine. Orthopedic surgeons and sports medicine professionals have established return-to-sports […]

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Synthetic joint lubricant holds promise for osteoarthritis

A new type of treatment for osteoarthritis, currently in canine clinical trials, shows promise for eventual use in humans. The treatment, developed by Cornell University biomedical engineers, is a synthetic version of a naturally occurring joint lubricant that binds to the surface of cartilage in joints and acts as a cushion during high-impact activities, such as running. “When the production […]

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Young athletes may need one-year break after knee surgery

After surgical reconstruction of the anterior cruciate ligament, young athletes are now recommended to undergo at least a year’s rehab and thorough testing before resuming knee-strenuous sport. Research shows that those who return to sport relatively soon after surgery incur a highly elevated risk of a second ACL injury. “What’s absolutely essential is to let the rehab take time. Every […]

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A deep-dive into the impact of arthritis drugs on gene expression: New analytical approach could serve as powerful tool to evaluate and compare treatments

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present their new approach and findings in PLOS Computational Biology. People with rheumatoid arthritis often receive medications that target and inhibit Tumor-Necrosis Factor (TNF), a protein involved in the painful […]

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Exercise helps prevent cartilage damage caused by arthritis

Exercise helps to prevent the degradation of cartilage caused by osteoarthritis, according to a new study from Queen Mary University of London. The researchers show for the first time how mechanical forces experienced by cells in joints during exercise prevent cartilage degradation by suppressing the action of inflammatory molecules which cause osteoarthritis. The study, published in the journal Osteoarthritis and […]

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