Mini-kidneys grown from stem cells provide new insights into kidney disease and potential therapies

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown ‘miniature kidneys’ in the laboratory that could be used to better understand how kidney diseases develop in individual patients. The mini kidneys, known as kidney organoids, were grown outside the body from skin cells derived from a single patient who has polycystic kidney disease, one […]

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New insights into young men’s sexting practices in youth sexting culture

Drawing on findings from a qualitative study published by the Journal of Youth Studies, new research from Dr. Emily Setty explores young men’s sexting practices and how they position themselves within youth sexting culture in terms of masculine heterosexuality. Young people who engage in sexting—the digital exchange of personal sexual messages and images—are considered at risk of potentially irreparable psychological, […]

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Snout dated: Slow-evolving elephant shark offers new insights into human physiology

The mineralocortoid receptor (MR) regulates water and sodium transport throughout cells and tissues, which is critical for controlling blood pressure and so, not surprisingly, the MR is common to all vertebrate animals. Aldosterone, which is a physiological steroid for land vertebrate MRs, evolved in lungfish (forerunners of land vertebrates), suggesting that the evolution of aldosterone was important in the conquest […]

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Computational model of a human kinase may provide insights for cancer treatment

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers. The initiation and progression of cancer cells occur when molecular signals involved in cellular proliferation go awry. MEK1 plays an essential role in signaling within both healthy and cancer cells. While much is known about the key […]

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Micro-computed tomography provides new insights into Paget’s disease

A MedUni Vienna study group led by Peter Pietschmann from the Institute of Pathophysiologyand Allergy Research in cooperation with the University of Vienna and the Museum of Natural History Vienna has made a detailed analysis of the microarchitecture of bones affected by the bone metabolic disease known as Paget’s disease. High-resolution micro-computed tomography techniques offer insights into the course of […]

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Pediatric health researchers offer insights for RSV vaccine

In healthy adults, RSV, or respiratory syncytial virus, feels like the common cold with a runny nose, chest congestion and cough. However, it is the second leading cause of death in infants. In fact, nearly 40 percent of infants who contract this widespread virus develop severe bronchiolitis or pneumonia, with 1 to 3 percent hospitalized. Each year, there are about […]

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Genetic study provides novel insights into the evolution of skin color

Skin colour is one of the most visible and variable traits among humans and scientists have always been curious about how this variation evolved. Now, a study of diverse Latin American populations led by UCL geneticists has identified new genetic variations associated with skin colour. The study, published in the journal Nature Communications, found that the variation of light skin […]

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