High-risk pregnancy: The interferon effect: Discovery of a cellular mechanism involved in abnormal placental development during some high-risk pregnancies

High-risk pregnancies occur frequently and may be caused by various factors. It is estimated that 10 to 20% of pregnant women miscarry during their first trimester of pregnancy. Slow fetal growth may also arise as a result of maternal infection with certain microbes, parasites or viruses (such as toxoplasmosis or infection with rubella virus, cytomegalovirus, herpes or Zika) or because […]

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Congo confirms 1st Ebola case in city of Goma

The Congolese Health Ministry is confirming Congo’s first Ebola case in the city of Goma, home to more than 2 million people. The regional capital in eastern Congo borders neighboring Rwanda, which has been preparing for possible cases since an outbreak began nearly a year ago. The person with the confirmed case announced late Sunday is a pastor who had […]

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Superbug virulence regulatory mechanism revealed: Pave ways for developing new antibiotics

As antibiotic resistance is growing and posing a threat on public health, developing new antibiotics has become more urgent than ever. Researchers at City University of Hong Kong (CityU) have recently revealed the virulence regulatory mechanism in Pseudomonas aeruginosa, a superbug which is common in patients with a weak immune system and is resistant to many antibiotics. The findings pave […]

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Deadly tick-borne virus cured with experimental flu drug, in mice: Bourbon virus has sickened people in Kansas, Missouri, Oklahoma

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness. Now, researchers at Washington University School of Medicine in St. Louis have identified an experimental antiviral drug that cures mice infected with the potentially lethal virus. The drug, favipiravir, […]

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Immunotherapy drug found safe in treating cancer patients with HIV, study suggests: Researchers seek to break down HIV exclusions in cancer clinical trials

The results of a study led by physicians at Fred Hutchinson Cancer Research Center showed that patients living with HIV and one of a variety of potentially deadly cancers could be safely treated with the immunotherapy drug pembrolizumab, also known by its brand name, KEYTRUDA®. During an ASCO presentation concurrent with release of a study in JAMA Oncology, Fred Hutch […]

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New findings could lead to improved vaccinations against sexually transmitted infections

In a study published today in the Nature Communications, researchers from King’s College London have shown how skin vaccination can generate protective CD8 T-cells that are recruited to the genital tissues and could be used as a vaccination strategy for sexually transmitted infections (STIs). One of the challenges in developing vaccines for STIs, such as HIV or herpes simplex virus, […]

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Over-fed bacteria make people sick

In a new hypothesis, a CRC 1182 research team suggests that inflammatory diseases are caused by an over-supply of food, and the associated disturbance of the intestine’s natural bacterial colonization. Since the end of the Second World War, along with the growing prosperity and the associated changes in lifestyle, numerous new and civilisation-related disease patterns have developed in today’s industrialised […]

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Cell-killing proteins suppress listeria without killing cells

New North Carolina State University research shows that key proteins known for their ability to prevent viral infections by inducing cell death can also block certain bacterial infections without triggering the death of the host cells. Rather than killing host cells infected by Listeria in the gastrointestinal tract, the RIPK3 and MLKL proteins recognize the chemical composition of the bacteria […]

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Congo's Ebola outbreak might be declared global emergency

A top Red Cross official said Friday he’s “more concerned than I have ever been” about the possible regional spread of the Ebola virus in Congo after a recent spike in cases. Emanuele Capobianco spoke by phone ahead of a key World Health Organization meeting in Geneva later Friday about whether to declare the deadly Ebola outbreak in northeastern Congo […]

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International aid helps Mozambique fight cholera in Beira

As Mozambique battles to control a fast-spreading cholera outbreak in the cyclone-hit central city of Beira, international assistance is arriving. The number of cholera cases jumped to 271 over the weekend although no deaths from the disease had been reported. More than 500 people have died in Mozambique from Cyclone Idai , which slammed into Beira more than two weeks […]

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