Cell-killing proteins suppress listeria without killing cells

New North Carolina State University research shows that key proteins known for their ability to prevent viral infections by inducing cell death can also block certain bacterial infections without triggering the death of the host cells. Rather than killing host cells infected by Listeria in the gastrointestinal tract, the RIPK3 and MLKL proteins recognize the chemical composition of the bacteria […]

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Parkinson’s clues seen in tiny fish could aid quest for treatments

Parkinson’s patients could be helped by fresh insights gained from studies of tiny tropical fish. Research using zebrafish has revealed how key brain cells that are damaged in people with Parkinson’s disease can be regenerated. The findings offer clues that could one day lead to treatments for the neurological condition, which causes movement problems and tremors. Parkinson’s occurs when specialised […]

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Exercise helps prevent cartilage damage caused by arthritis

Exercise helps to prevent the degradation of cartilage caused by osteoarthritis, according to a new study from Queen Mary University of London. The researchers show for the first time how mechanical forces experienced by cells in joints during exercise prevent cartilage degradation by suppressing the action of inflammatory molecules which cause osteoarthritis. The study, published in the journal Osteoarthritis and […]

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Copycat fungus deceives immune system and deactivates body’s response to infection

Fungus can imitate signals from our immune system and prevent our body from responding to infection, new research from the University of Sheffield has found. Life-threatening fungal infection is a major killer of people with immune system problems such as blood cancers, HIV infection or following organ transplant. The new study focused on one of the most dangerous infections for […]

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Hydrogel contact lens to treat serious eye disease

Researchers at the University of New Hampshire have created a hydrogel that could one day be made into a contact lens to more effectively treat corneal melting, a condition that is a significant cause for blindness world-wide. The incurable eye disease can be initiated by a number of different causes such as autoimmune diseases (like rheumatoid arthritis, Lupus, or Stevens-Johnson […]

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Study: Excessive salt-values in the case of skin allergies and atopic dermatitis demonstrated

Increased salt concentration in lesional skin demonstrated Allergies and skin diseases such as neurodermatitis are widely used in industrial countries such as Germany. About every third Person developed in the course of his life, an Allergy, on average, every tenth child suffers from eczema. The causes that lead to Allergy are still unknown. A German research team proved in a […]

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How a fungus can cripple the immune system: Research team clarifies the mechanism of gliotoxin, a mycotoxin from the fungus Aspergillus fumigatus

It is everywhere — and it is extremely dangerous for people with a weakened immune system. The fungus Aspergillus fumigatus occurs virtually everywhere on Earth, as a dark grey, wrinkled cushion on damp walls or in microscopically small spores that blow through the air and cling to wallpaper, mattresses and floors. Healthy people usually have no problem if spores find […]

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New hope for stem cell approach to treating diabetes: Insulin-producing cells more responsive to fluctuating glucose levels

Scientists working to develop more effective treatments for diabetes are turning to stem cells. Such cells can be transformed into cells that produce insulin, the hormone that controls blood sugar. But there’s a major challenge: the amount of insulin produced by theses cells is difficult to control. Now, by tweaking the recipe for coaxing human stem cells into insulin-secreting beta […]

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Scientists create a renewable source of cancer-fighting T cells

A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells — which can give rise to every cell type in the body and which can be grown indefinitely in the lab — into becoming mature T cells capable of killing tumor cells. The technique uses structures called artificial thymic organoids, which work by […]

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