Study links progenitor cells to age-related prostate growth

The prostates of older mice contain more luminal progenitor cells—cells capable of generating new prostate tissue—than the prostates of younger mice, UCLA researchers have discovered. The observation, published in Cell Reports, helps explain why, as people age, the prostate tends to grow, leading to an increased risk for prostate cancer and other conditions. “Understanding what’s causing the prostate to grow […]

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Toxin responsible for Legionella growth identified

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps legionella grow inside human cells. SidJ hijacks human protein Calmodulin to its own advantage in one of the classic examples of pathogenic bacteria exploiting the […]

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Protein ‘spat out’ by cancer cells promotes tumor growth

Prostate cancer cells change the behaviour of other cells around them, including normal cells, by ‘spitting out’ a protein from their nucleus, new research has found. The tiny pieces of protein are taken up by the other cells, provoking changes that promote tumour growth and—the researchers believe—help the cancer hide from the body’s immune system. The process has been captured […]

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Researchers block two cancer cell signaling pathways and slow tumor growth

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy in the United States, according to new research from a team led by Case Western Reserve University School of Medicine. The group identified the pathways using advanced computational and genetic analyses of tumor biopsies from EAC patients. They found […]

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How chronic stress boosts cancer cell growth

Chronic stress, which a person has consistently over a long period of time, affects mental and emotional well-being as well as physical health. Studies have tied chronic stress to accelerated cognitive impairment, a higher risk of heart problems, and problems with gut health. Previous research also suggests that exposure to stress could speed up the growth of cancer through its […]

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New knowledge of pubertal growth

In monitoring and prediction of children’s growth, the spurt in puberty is often considered too variable to be predictable. However, new findings and methods enable a better picture of how children and adolescents grow, especially during puberty. “Growth reflects health and can be a diagnostic indicator, capable of revealing both diseases and psychosocial problems. Measuring and monitoring height and weight […]

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