Machine learning’s next frontier: Epigenetic drug discovery

Machine learning’s powerful ability to detect patterns in complex data is revolutionizing how we drive, how we diagnose disease and now, how we discover new drugs. Scientists at Sanford Burnham Prebys Medical Discovery Institute have developed a machine-learning algorithm that gleans information from microscope images—allowing for high-throughput epigenetic drug screens that could unlock new treatments for cancer, heart disease, mental […]

Read more

Drug reduces risk of pneumonia in newborn mice

The underdeveloped lungs and immune systems of premature babies put them at high risk of potentially deadly pneumonia. Now, a study from Washington University School of Medicine in St. Louis has found, in mice, that an inhaled drug promotes the development of lung immunity and reduces the risk of pneumonia. The findings, published Aug. 14 in Science Advances, suggest that […]

Read more

Immunotherapy drug could help women with aggressive breast cancer

Immunotherapy drug could halt the return of the ‘most aggressive form of breast cancer’ and ‘save thousands of lives’ Women with triple negative breast cancer were given the drug Keytruda  Keytruda was taken alongside chemo to shrink tumours before surgery More than 60% of the patients showed no sign of cancer after the operation An immunotherapy drug could prevent a […]

Read more

Why a plan to lower prescription drug prices should not be piecemeal

Demand for prescription medications in the U.S. is at an all time high, given that 50% of adults have at least one chronic condition, and 25% have two or more. Sixty percent of the population, and 90% of Medicare beneficiaries have taken at least one prescription medication in the past month. Rising health care costs over time are leading to […]

Read more

Holes in the immune system left unrepaired despite drug therapy

If they don’t receive antiretroviral therapy (ART), most HIV patients see a progressive weakening of their immune system. But a very small percentage of patients—0.3%—spontaneously control the virus themselves, without ART. Could an explanation lay partly in the sets of genes expressed by scarce white blood cells that recognize HIV? Yes, according to a study published in Nature Immunology and […]

Read more

Discovery of mechanism behind precision cancer drug opens door for more targeted treatment

New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy. PARP inhibitors are molecular targeted cancer drugs used to treat women with ovarian cancer who have the BRCA1 and BRCA2 gene mutations. The drugs are showing promise in late-stage clinical trials for breast cancer, prostate cancer and pancreatic cancer […]

Read more

Suit: Generic drug makers used code to fix price increases

A lawsuit says representatives of some of the nation’s largest generic drug manufacturers used code words to collude with competitors to divvy up market share and coordinate price increases. The code came in emails included in the lawsuit filed last month by attorneys general from more than 40 states. The 510-page federal lawsuit filed in Connecticut was released in full […]

Read more

Anti hypertensive drug use was associated with a decreased dementia risk

Various clinical trials indicate what effects can be expected from standardized intervention programs on the basis of existing evidence. Little is known about the way in which such programs can be implemented in actual care practice. However, it may be possible to use data from clinical practice to estimate the potential of drug prescriptions to delay or reduce the development […]

Read more

Health Canada’s drug safety warnings not consistent with other countries’: report

Health Canada needs to be more consistent with three other countries when it comes to issuing warnings about the safety risks of certain medications, especially if the jurisdictions with similar demographics have already advised patients taking the same drugs, a University of British Columbia professor says. Related Your drugs may have drugs in them: safety group finding meth in cocaine, […]

Read more

Poll: Many blame drug firms for opioid crisis

About two-thirds of Americans believe drug companies are to blame for the opioid crisis, although nearly as many hold drug users themselves responsible, a new poll finds. The Associated Press-NORC Center for Public Affairs Research poll showed many people also fault doctors who prescribed opioid pain pills and government officials who haven’t done enough to expand addiction treatment and arrest […]

Read more
1 2 3 4