Vicious circles: Ring-shaped DNA provides cancer cells with a malignant twist

Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape. Building upon previous revelatory work, a team of scientists, led by researchers at University of California San Diego, the UC San Diego branch of the Ludwig Institute for Cancer Research, Stanford University and the Howard Hughes Medical Institute, report that in cancer, distinct doughnut-shaped […]

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Inequality now extends to people’s DNA

It’s well known that some areas of the UK are poorer than others. These include Wales and northern Britain, which used to be coal-mining areas. Now we have discovered that these regional economic inequalities are in line with regional differences in DNA as well—with people becoming increasingly clustered by certain types of genetics. Genetic clustering has existed in all past […]

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Cell-free DNA detects pathogens and quantifies damage

A common problem in diagnosing infectious disease is that the presence of a potential pathogen in the body does not necessarily mean the patient is sick. This can be particularly challenging for the treatment of organ transplant recipients, who often grapple with infection as well as complications related to immunosuppression. A new Cornell study, “A Cell-Free DNA Metagenomic Sequencing Assay […]

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Jeffrey Epstein was devising plan to seed the human race with his DNA

Jeffrey Epstein was devising a plan to seed the human race with his DNA by impregnating women at his New Mexico ranch and wanted to have his penis and head frozen after he died Jeffrey Epstein planned to have 20 women at a time impregnated on in Santa Fe ranch, sources told the Times The moneyman claimed to spend $20 […]

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Lung cell patches its own DNA on the fly to survive influenza

Scientists at Duke University have identified one kind of lung cell that can hustle to repair its damaged DNA and survive an attack of the influenza A virus while other kinds of cells around it die in droves. The finding reveals more about the battle between cells and viruses at the smallest level, and also may provide some important clues […]

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First US murder conviction overturned using DNA, family tree evidence

An American man was exonerated Wednesday for a decades-old murder he did not commit, using evidence based on DNA and a genetic family tree, the first such result using a revolutionary investigative technique. Christopher Tapp, 43, had served 20 of his 30-year sentence for the 1996 rape and murder of Angie Dodge. On Wednesday, a court in the state of […]

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Determined DNA hunt reveals schizophrenia clue

An 18-year study using the DNA of thousands of people in India has identified a new clue in the quest for causes of schizophrenia, and for potential treatments. University of Queensland and Indian researchers searched the genomes of more than 3000 individuals and found those with schizophrenia were more likely to have a particular genetic variation. Professor Bryan Mowry from […]

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DNA tests for patients move closer with genome analysis advance

Diseases caused by genetic changes could be detected more readily thanks to an advance in DNA analysis software. The development will make it easier to integrate genetic testing into health care systems such as the UK’s National Health Service, which cares for around three million people affected by genetic diseases in the UK. The new tool can spot precise genetic […]

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Researchers relate DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are “on” or “off”, and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits. This research evidences that methylation levels in the gene involved in lipid metabolism -Lipoprotein lipase (LPL)- are higher in obese people with a metabolic disease in contrast to healthy people. “Since this […]

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