Research confirms nerve cells made from skin cells are a valid lab model for studying disease

The incidence of some neurological diseases—especially those related to aging, such as Alzheimer’s and Parkinson’s diseases—is increasing. To better understand these conditions and evaluate potential new treatments, researchers need accurate models that they can study in the lab. Researchers from the Salk Institute, along with collaborators at Stanford University and Baylor College of Medicine, have shown that cells from mice […]

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More proof high-fiber diets help prevent cancers, heart disease

(HealthDay)—A large, new analysis helps confirm that eating lots of grains, vegetables and fruit lowers your risk of dying early from cancer or heart disease. When compared with those who consume very little fiber, people at the high end of the fiber-eating spectrum saw their risk for dying from heart disease, stroke, type 2 diabetes and/or colon cancer plummet by […]

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Study reveals how much fiber we should eat to prevent disease

Researchers and public health organizations have long hailed the benefits of eating fiber, but how much fiber should we consume, exactly? This question has prompted the World Health Organization (WHO) to commission a new study. The results appear in the journal The Lancet. The new research aimed to help develop new guidelines for dietary fiber consumption, as well as reveal […]

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Undiplomatic immunity: Mutation causing arterial autoimmune disease revealed

Takayasu arteritis is a disease that mainly affects female Asians at a relatively young age. It involves chronic inflammation of the aorta, and potentially leads to fatal disruption of the structures through which blood flows from the heart. Although studies have suggested a genetic component to this disease, its mechanisms have remained opaque until now. A new study led by […]

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Skin Autofluorescence Predicts T2DM, Heart Disease, Mortality

WEDNESDAY, Dec. 5, 2018 — Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease (CVD), and mortality in the general population, according to a study published online Nov. 21 in Diabetologia. Robert P. van Waateringe, from the University of Groningen in the Netherlands, and colleagues conducted a prospective analysis involving 72,880 participants from the Dutch Lifelines Cohort Study who had […]

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Skin autofluorescence predicts T2DM, heart disease, mortality

(HealthDay)—Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease (CVD), and mortality in the general population, according to a study published online Nov. 21 in Diabetologia. Robert P. van Waateringe, from the University of Groningen in the Netherlands, and colleagues conducted a prospective analysis involving 72,880 participants from the Dutch Lifelines Cohort Study who had validated baseline skin autofluorescence values […]

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On the trail of rare genetic disease, scientists uncover key immune regulator

Scientists at Scripps Research have found an important immune system-regulating protein that in principle could be targeted to treat cancers and chronic viral infections. The scientists, in a study published November 12 in Nature Chemical Biology, set out to determine the function of a protein, ABHD12, whose absence causes a rare genetic disease featuring a host of brain and nerve […]

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Zebrafish help unlock mystery of motor neurone disease

Scientists from the University of Sheffield have successfully created zebrafish that carry the complex genetic change known to cause the most common genetic form of motor neurone disease (MND). The breakthrough will help to accelerate pioneering research and experimental drug trials to tackle the degenerative disease. Until now, research to better understand how the disease occurs and the trial of […]

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Study suggests way to prevent rare pulmonary disease

Research by Vanderbilt scientists suggests that it may be possible to prevent or even reverse pulmonary arterial hypertension (PAH), a rare, progressive disease characterized by narrowing of and high blood pressure in the small arteries of the lungs. A key player in PAH is the proangiogenic cell (PAC), a cell produced by the bone marrow that normally promotes the growth […]

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Colder, darker climates increase alcohol consumption and liver disease

Where you live could influence how much you drink. According to new research from the University of Pittsburgh Division of Gastroenterology, people living in colder regions with less sunlight drink more alcohol than their warm-weather counterparts. The study, recently published online in Hepatology, found that as temperature and sunlight hours dropped, alcohol consumption increased. Climate factors also were tied to […]

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