Diabetes before or during pregnancy linked to early heart disease in children

Children of mothers with diabetes have increased rates of early onset cardiovascular disease or CVD (conditions affecting the heart or blood vessels) from childhood up to the age of 40, finds a study from Denmark published by The BMJ today. The increased rates were more pronounced among children of mothers with a history of CVD or diabetic complications. If this […]

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Molecular bodyguards against Parkinson’s disease

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson’s disease. A disturbed relationship to these “bodyguards” leads to cell damage and the formation of Lewy bodies typical for Parkinson’s disease. The findings by researchers from the University of Basel’s Biozentrum have been published in Nature. Parkinson’s disease is one of the most […]

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Breast milk could help prevent heart disease caused by premature birth

Early use of breast milk could play a vital role in preventing heart disease in prematurely born infants, according to a paper led by researchers at RCSI (Royal College of Surgeons in Ireland) and the Rotunda Hospital. The review article, published in the journal Pediatric Research, was written in collaboration with researchers from Harvard Medical School, University of Oxford and […]

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Cells study helping to crack the code to Alzheimer’s disease

A study led by researchers at Monash University has opened up new hope for diagnosing and treating Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia in older people and, as there are no effective treatments, is one of the leading contributors to the global disease burden. Various genes have been implicated in the changes that happen in […]

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Researchers identify a molecular mechanism involved in Huntington’s disease

Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) described a mechanism, the increase of proteinaceous synthesis, which takes part in the degeneration of the type of neurons that are affected in Huntington’s disease, a genetic neurodegenerative disease. These results, published in the journal Brain, could help […]

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Many patients with iNPH develop Alzheimer’s disease, too

Up to one in five patients treated for idiopathic normal pressure hydrocephalus, iNPH, also develop Alzheimer’s disease, according to a new study from the University of Eastern Finland and Kuopio University Hospital. The researchers were able to predict the development of Alzheimer’s disease by using the Disease State Index, DSI, that combines patient-specific data from various sources. The results were […]

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Celiac disease screening for family members

Celiac disease is an immune reaction to eating gluten. A recent Mayo Clinic study found that this autoimmune disease tends to run in families. Researchers say screening family members of celiac disease patients could prevent long-term complications, such as nutritional deficiencies, development of new autoimmune conditions and small bowel malignancy. If one member of a family has celiac disease, there […]

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More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently published in the Journal of Post-Acute and Long-Term Care Medicine. Marjaana Koponen, Ph.D., of the Kuopio Research Center of Geriatric Care at the University of Eastern Finland, and colleagues used a nationwide exposure-matched cohort to […]

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Study shows biomarker accurately diagnoses deadly infant disease

A diagnostic study of 136 premature infants found that a protein involved in managing harmful bacteria in the human intestine is a reliable biomarker for the noninvasive detection of necrotizing enterocolitis (NEC). Led by researchers and clinicians at LSU Health New Orleans School of Medicine, this is one of the largest prospective clinical studies in premature infants yet. Results of […]

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