Database to support infectious disease research

A new database PathoPhenoDB facilitates the search for associations between infectious diseases, the pathogens that cause them, the resulting clinical signs and symptoms, and the drugs that can treat them. It also contains information on the proteins and genetic changes that can make pathogens resistant to treatment with certain drugs. Developed by researchers at KAUST in collaboration with the University […]

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Why young females with obesity are at early risk for cardiovascular disease

In the face of obesity, the sex hormone progesterone that helps females get and stay pregnant appears to also put them at increased, early risk for cardiovascular disease, investigators report. Premenopausal women are considered protected from cardiovascular disease, but evidence indicates obesity can negate those benefits, and in fact put them at even higher risk than men, but just how […]

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New guideline on Parkinson’s disease aimed at physicians and people with Parkinson’s

A comprehensive new Canadian guideline provides practical guidance for physicians, allied health professionals, patients and families on managing Parkinson disease, based on the latest evidence. The guideline is published in CMAJ (Canadian Medical Association Journal), accompanied by an easy-to-reference infographic and podcast. Parkinson disease is a debilitating, progressive neurological condition that affects quality of life for patients and their caregivers. […]

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At least five dead in US from vaping-related lung disease

At least five people have died in the United States after vaping, officials said Friday, in an outbreak that has sickened hundreds with severe pulmonary disease and left several teens in induced comas. Federal officials said that no single substance has been found to be present in all the laboratory samples being examined, however investigators in New York said they […]

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Small reductions in blood pressure ‘slash the risk of heart disease’

Small reductions in blood pressure and cholesterol ‘could cut heart disease risk by up to 80 per cent even in healthy people’ Scientists analysed the heart health of more than 438,000 people  They said good heart health ‘pays very big dividends’  Expert urges people to take advantage of free health checks on the NHS  Even small reductions in blood pressure and […]

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Retina-on-a-chip provides powerful tool for studying eye disease

The development of a retina-on-a-chip, which combines living human cells with an artificial tissue-like system, has been described today in the open-access journal eLife. This cutting-edge tool may provide a useful alternative to existing models for studying eye disease and allow scientists to test the effects of drugs on the retina more efficiently. Many diseases that cause blindness harm the […]

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Mini-kidneys grown from stem cells provide new insights into kidney disease and potential therapies

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown ‘miniature kidneys’ in the laboratory that could be used to better understand how kidney diseases develop in individual patients. The mini kidneys, known as kidney organoids, were grown outside the body from skin cells derived from a single patient who has polycystic kidney disease, one […]

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Parkinson’s disease: These mouth difficulties could mean you are at risk

Parkinson’s develops when cells in the brain stop working properly and are lost over time. These brain cells produce a chemical called dopamine. Symptoms start to appear when the brain can’t make enough dopamine to control movement properly. People with Parkinson’s disease commonly experience tremor (shaking), slowness of movement and rigidity (muscle stiffness) – but there are many other symptoms […]

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Blood test is 94% accurate at identifying early Alzheimer’s disease

Up to two decades before people develop the characteristic memory loss and confusion of Alzheimer’s disease, damaging clumps of protein start to build up in their brains. Now, a blood test to detect such early brain changes has moved one step closer to clinical use. Researchers from Washington University School of Medicine in St. Louis report that they can measure […]

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UK tick-borne Lyme disease cases may be three times higher than previous estimates

New cases of tick-borne Lyme disease in the UK may be three times higher than previous estimates suggest, and might top 8000 in 2019, based on these figures, concludes research published in the online journal BMJ Open. Lyme disease is a bacterial (Borrelia) infection passed on through the bite of an infected tick. It has become the most common tick-borne […]

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