Adipocyte glucocorticoid receptors play a role in developing steroid diabetes

Steroids are used for treating various diseases such as allergic disorders, but they occasionally cause adverse effects, such as steroid diabetes and other metabolic disturbances. Since steroids act throughout the body, how these adverse effects are caused and by which organ are not well understood. Researchers at Osaka University focused on glucocorticoid receptors (GRs), the receptors for the body’s endogenous […]

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General anesthesia is unlikely to have lasting effects on the developing brains of young children: study

A single hour of general anaesthesia in early infancy—longer than is necessary to perform the most common types of minor surgeries in childhood—does not result in measurable neurodevelopmental or behavioural problems up to the age of 5 years, according to the first randomised trial of its kind involving 722 infants in seven countries, published in The Lancet. The trial provides […]

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Researchers developing nonopioid drug for chronic pain

Researchers from the Virginia Tech School of Neuroscience are teaming with the University of California San Diego and the U.S. National Institutes of Health to develop a drug—now in its earliest stages—that can treat certain types of chronic pain without the addictive consequences of opioids. The drug compound, known as ML351, was discovered by researchers from the NIH, part of […]

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