New evidence shows cytotoxic T cells can identify, invade, and destroy targets of large mass like T. gondii tissue cysts

CD8+ cytotoxic T lymphocytes can kill host cells infected with various microorganisms as well as single individual cancer cells through direct cell-to-cell contact, but their ability to destroy a target of large mass remains unexplored. A study in The American Journal of Pathology provided novel evidence on the capability of the immune system to eliminate large parasite-filled cysts associated with […]

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Research: Many common drugs slowly destroy the intestinal flora

New adverse side-effect is discovered in one of every four drug Antibiotics are known to be a bacteria killer, the combat is both useful as well as harmful bacteria dimensions. A recent study revealed that, in addition, more than one out of every four drug naturally in the human gut bacteria influenced. This hitherto unknown side effect could have long-term […]

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Antibody therapy training phagocytes to destroy tumors now tested on patients

Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumours in several mouse models, and the development of the therapy has now progressed to patient testing in a phase I/II clinical trial. One reason behind many unsuccessful […]

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