Breaking down pathological protein aggregates

Aggregates of the protein alpha-synuclein in the nerve cells of the brain play a key role in Parkinson’s and other neurodegenerative diseases. These protein clumps can travel from nerve cell to nerve cell, causing the disease to progress. A team of researchers led by ETH scientists have now discovered how the body can rid itself of these damaging aggregates. Their […]

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Anti hypertensive drug use was associated with a decreased dementia risk

Various clinical trials indicate what effects can be expected from standardized intervention programs on the basis of existing evidence. Little is known about the way in which such programs can be implemented in actual care practice. However, it may be possible to use data from clinical practice to estimate the potential of drug prescriptions to delay or reduce the development […]

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Poll: Many adults worried about developing dementia

(HealthDay)—Many adults are worried about developing dementia and about half report taking steps to maintain or improve memory, according to a report published by the National Poll on Healthy Aging. Preeti Malani, M.D., from the National Poll on Healthy Aging team, and colleagues surveyed 1,028 adults aged 50 to 64 years about their memory, concerns about developing dementia, and participation […]

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Ragweed compounds could protect nerve cells from Alzheimer’s

As spring arrives in the northern hemisphere, many people are cursing ragweed, a primary culprit in seasonal allergies. But scientists might have discovered a promising new use for some substances produced by the pesky weed. In ACS’ Journal of Natural Products, researchers have identified and characterized ragweed compounds that could help nerve cells survive in the presence of Alzheimer’s disease […]

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Everyone can minimize his risk of Dementia: of those WHO Guide shows how to do it

50 million people worldwide have dementia, and in the next few years there will probably be many more. The WHO has now presented for the first time guidelines and asked the States. But for each and every Individual can prevent it. Who moves more, and with the Smoking stops, it can prevent also a dementia disease. The world health organization […]

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Alzheimer’s disease is a ‘double-prion disorder’: Self-propagating amyloid and tau prions found in post-mortem brain samples, with highest levels in patients who died young

Two proteins central to the pathology of Alzheimer’s disease act as prions — misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape — according to new UC San Francisco research. Using novel laboratory tests, the researchers were able to detect and measure specific, self-propagating prion forms of the proteins amyloid […]

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Low scam awareness in old age may be an early sign of impending cognitive decline and dementia

Low scam awareness in older people is associated with risk for developing Alzheimer dementia or mild cognitive impairment in the future. These findings suggest that changes in social judgment occur before changes in thinking or memory are recognizable. Findings from a prospective cohort study are published in Annals of Internal Medicine. Identifying predictors of dementia and mild cognitive impairment is […]

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MIND diet: New diet plan reduces the risk of dementia significantly

Protects healthy diet before the cognitive decline? Doctors tested the effects of different forms of nutrition and diet on cognitive health, to find out whether a special diet may protect against the emergence of a dementia. The scientists from the Columbia University found in their recent study that proper nutrition appears to protect against the development of dementia. The experts […]

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