For patients with diabetes, ticagrelor reduced heart attacks, strokes: Benefits particularly favorable in patients with prior coronary artery stenting; patients also experienced increased risk of bleeding

In late-breaking clinical trial results presented in a Hot Line Session today at the European Society of Cardiology Congress 2019, investigators from Brigham and Women’s Hospital and Greater Paris University Hospitals — AP-HP/Université de Paris presented the results from The Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study (THEMIS), a clinical trial sponsored by AstraZeneca that […]

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Insight into cells’ ‘self-eating’ process could pave the way for new dementia treatments

Cells regularly go through a process called autophagy—literally translated as ‘self-eating’ – which helps to destroy bacteria and viruses after infection. When it works, this process counteracts neurodegenerative conditions such as dementia and Huntington’s Disease, by getting rid of unwanted proteins and their resultant harm to cells. But when autophagy fails or defects occur, it can give rise to such […]

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Pinpointing how cells regulate long-lasting memories

The brain has a knack for safekeeping our most treasured memories, from a first kiss to a child’s birth. In a new study in mouse cells, Columbia neuroscientists have mapped some of the molecular machinery that helps the brain maintain these kinds of long-term memories. By observing the activity of nerve cells of the brain, called neurons, that were extracted […]

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How to protect the brain: Study proves you can fight off dementia

And it can be achieved by following just seven easy steps – preventing both cardiovascular and Alzheimer’s disease, according to scientists. The programme recommends controlling blood pressure and cholesterol, reducing blood sugar and getting physically active. Known as Life’s Simple 7, it also advises a healthy diet, losing excess weight and giving up smoking. Sticking to it has already been shown to […]

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High cholesterol could TRIPLE old people’s dementia risk, study warns

High cholesterol could TRIPLE risk of dementia in the over-60s as doctors urge the elderly to cut down on cheese and butter to protect their brains Researchers in Indonesia said a history of high cholesterol was a ‘major risk’ Small study found people with high cholesterol had a 50/50 chance of dementia Cholesterol is raised by foods with a lot […]

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Alzheimer’s protein is likely held together with many weak chemical interactions: Model reveals new role for overlooked electron relationships

The chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide a new way for researchers to understand proteins that cause disease and help them gain insights into the fundamentals of chemistry. Chemists at the University of Tokyo modeled the building blocks of the protein structure that causes Alzheimer’s disease, […]

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Robot puppy comforts dementia patients

Robot puppy comforts dementia patients with its wagging tail, grunts and lifelike head movements – but none of the clean-up Tombot, a Los Angeles company, has collaborated with the makers of Muppets to design a ‘realistic’ robot dog  They are currently testing the automated animal with Alzheimer’s patients in Thousand Oaks, California  Jenny, the test dog, resembles a yellow Labrador retriever […]

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Moments of clarity in dementia patients at end of life: Glimmers of hope?

It happens unexpectedly: a person long thought lost to the ravages of dementia, unable to recall the events of their lives or even recognize those closest to them, will suddenly wake up and exhibit surprisingly normal behavior, only to pass away shortly thereafter. This phenomenon, which experts refer to as terminal or paradoxical lucidity, has been reported since antiquity, yet […]

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Parkinson’s disease: The five stages of Parkinson’s disease and how to spot the condition

Parkinson’s disease is characterised by the loss of cells of the brain or spinal cord, which over times leads to dysfunction and disability. It affects predominantly dopamine-producing neutrons in a specific area of the brain. The cause of Parkinson’s remains largely unknown and although there is no cure there are many treatment options including medications and surgery. Stage one The […]

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Commonly prescribed drugs may up dementia risk: Study

According to the research published in the journal JAMA Internal Medicine, out of the 58,769 patients with dementia, 63 per cent were women. The average age of the patients was 82. Drugs widely prescribed to treat a variety of conditions including gastrointestinal disorders and bladder conditions may significantly increase the risk of dementia in older adults. The researchers from University […]

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