Scientists slam Chinese CRISPR babies research after manuscript released

The gene editing performed on Chinese twins last year meant to immunize them against HIV may have failed in its purpose and created unintended mutations, scientists said Tuesday after the original research was made public for the first time. Excerpts from the manuscript were released by the MIT Technology Review for the purpose of showing how Chinese biophysicist He Jiankui […]

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Tweaked CRISPR in neurons gives scientists new power to probe brain diseases

A team of scientists at UC San Francisco and the National Institutes of Health have achieved another CRISPR first, one which may fundamentally alter the way scientists study brain diseases. In a paper published August 15 in the journal Neuron, the researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity […]

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CRISPR baby mutation significantly increases mortality

A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them fend off HIV infection, is also associated with a 21% increase in mortality in later life, according to an analysis by University of California, Berkeley, scientists. The researchers scanned more than 400,000 genomes and associated health records contained in a […]

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New CRISPR tool executes multiple edits simultaneously, leading to unique partnership to deliver cancer treatments

Scientists at Christiana Care Health System’s Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal. The tool can rapidly reproduce, in a human DNA sample, the unique […]

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Experts call for halt to CRISPR editing that allows gene changes to pass on to children

Remember the global outrage four months ago at world-first claims a researcher had used the gene editing tool CRISPR to edit the genomes of twin girls? The molecular scissors known as CRISPR (CRISPR/cas9 in full) allow scientists to modify DNA with high precision and greater ease than previous technologies. Now researchers from the USA, Europe, China and New Zealand have […]

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Why Are Scientists So Upset About the First Crispr Babies?

A Chinese scientist recently claimed he had produced the world’s first gene-edited babies, setting off a global firestorm. If true — the scientist has not yet published data that would confirm it — his actions would be a sensational breach of international scientific conventions. Although gene editing holds promise to potentially correct dangerous disease-causing mutations and treat some medical conditions, […]

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‘Science is not ready’: China scientist’s gene editing slammed as unethical, dangerous

The Chinese scientist who says he helped make the world’s first gene-edited babies is being slammed by his own university, as well as scientists around the world, for unethical conduct. He Jiankui said twin girls born earlier this month have altered DNA to help resist any possible future infection of HIV. The research hasn’t been independently verified or peer reviewed, […]

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