Gene levels could help predict prognosis for colorectal cancer

Levels of a gene that helps the immune system differentiate the good cells from the bad could be a good indicator of prognosis in people with colorectal cancers, Medical College of Georgia researchers report. Looking at 15 genes known to be associated with colorectal cancers—eight associated with lower survival rates and seven with higher—the researchers found that one gene, CCR4, […]

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Nearly 30 types of gut bacteria linked to colorectal cancer

Nearly 30 types of gut bacteria are linked to colorectal cancer, new studies find Researchers found higher levels of nearly 30 different types of bacteria in colorectal cancer patients compared to healthy individuals One was Fusobacterium nucleatum, an oral bacterium that plays a role in periodontal disease  Another breaks down choline, an essential nutrient found in meat, and turns it […]

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Gene involved in colorectal cancer also causes breast cancer

Rare mutations in the NTHL1 gene, previously associated with colorectal cancer, also cause breast cancer and other types of cancer. Researchers from Radboud university medical center, Leiden University Medical Center and the Princess Máxima Center in the Netherlands report this new multi-tumor syndrome, in collaboration with international colleagues, in Cancer Cell. Nicoline Hoogerbrugge, professor of Hereditary Cancer at Radboud university […]

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Loss of two genes drives a deadly form of colorectal cancer, reveals a potential treatment

Colorectal cancers arise from earlier growths, called polyps, found on the inner surface of the colon. Scientists are now learning that polyps use two distinct molecular pathways as they progress to cancer, called the “conventional” and “alternative” pathways. The latter leads to an often treatment-resistant tumor, called serrated colorectal cancer; thus, distinguishing between these two cancer types holds implications for […]

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