Researchers unlock cancer cells’ feeding mechanism, central to tumor growth: The findings could lead to new treatments by blocking tumor growth at its roots

An international team led by researchers from the University of Cincinnati and Japan’s Keio and Hiroshima universities has discovered the energy production mechanism of cancerous cells that drives the growth of the nucleolus and causes tumors to rapidly multiply. The findings, published Aug. 1 in the journal Nature Cell Biology, could lead to the development of new cancer treatments that […]

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Evidence a cancer drug may be extended to many more patients

A new molecular mechanism discovered by UT Southwestern researchers indicates that drugs currently used to treat less than 10 percent of breast cancer patients could have broader effectiveness in treating all cancers where the drugs are used, including ovarian and prostate cancers. The new study also revealed a potential biomarker indicating when these drugs, called PARP inhibitors, can be unleashed […]

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Strain of common cold virus could revolutionize treatment of bladder cancer

A strain of the common cold virus has been found to potentially target, infect and destroy cancer cells in patients with bladder cancer, a new study in the medical journal Clinical Cancer Research reports. No trace of the cancer was found in one patient following treatment with the virus. Researchers from the University of Surrey and Royal Surrey County Hospital […]

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Obese people outnumber smokers two to one

New figures from Cancer Research UK show that people who are obese now outnumber people who smoke two to one in the UK*, and excess weight causes more cases of certain cancers than smoking, as the charity urges Government action to tackle obesity. Almost a third of UK adults are obese** and, while smoking is still the nation’s biggest preventable […]

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Immunotherapy drug found safe in treating cancer patients with HIV, study suggests: Researchers seek to break down HIV exclusions in cancer clinical trials

The results of a study led by physicians at Fred Hutchinson Cancer Research Center showed that patients living with HIV and one of a variety of potentially deadly cancers could be safely treated with the immunotherapy drug pembrolizumab, also known by its brand name, KEYTRUDA®. During an ASCO presentation concurrent with release of a study in JAMA Oncology, Fred Hutch […]

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New blood test uses DNA ‘packaging’ patterns to detect multiple cancer types

Researchers at the Johns Hopkins Kimmel Cancer Center have developed a simple new blood test that can detect the presence of seven different types of cancer by spotting unique patterns in the fragmentation of DNA shed from cancer cells and circulating in the bloodstream. In a proof-of-concept study, the test, called DELFI (DNA evaluation of fragments for early interception), accurately […]

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Conquering cancer’s infamous KRAS mutation

KRAS is one of the most challenging targets in cancer. Despite its discovery more than 60 years, researchers still struggle to inhibit its mutated form — earning its reputation as “undruggable.” Yet, the hunt for an Achilles’ heel continues, as cancers driven by KRAS mutations are both common and deadly. Now, scientists from Sanford Burnham Prebys and PHusis Therapeutics have […]

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Biologists design new molecules to help stall lung cancer: Scientists tie tumor growth to heme availability, build peptide to ‘hijack’ uptake

University of Texas at Dallas scientists have demonstrated that the growth rate of the majority of lung cancer cells relates directly to the availability of a crucial oxygen-metabolizing molecule. In a preclinical study, recently published in Cancer Research, biologist Dr. Li Zhang and her team showed that the expansion of lung tumors in mice slowed when access to heme — […]

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Funds to pay colorectal cancer screening in the future from 50 years ago

Colorectal cancer screening men can have in the future from just 50 years, at the expense of the statutory health insurance a colonoscopy. Previously, the investigation had been offered to the Insured by law until the age of 55 years, shared the Felix-Burda-Stiftung. Officially, the deal starts on Friday (19. April), because of the decision of the competent body, joined […]

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Discovery of oral cancer biomarkers could save thousands of lives

Oral cancer is known for its high mortality rate in developing countries, but an international team of scientists hope its latest discovery will change that. Researchers from the University of Otago, New Zealand, and the Indian Statistical Institute (ISI), Kolkata, have discovered epigenetic markers that are distinctly different in oral cancer tissues compared to the adjacent healthy tissues in patients. […]

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