Blood-clotting protein and blood platelets promote immune evasion, cancer progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer. The findings show how thrombin, a clotting protein in the blood, causes blood platelets to release transforming […]

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Circular RNA limits skin cancer spread

A mysterious piece of genetic material restrains the spread of skin cancer cells, but is frequently lost as they mature, a new study finds. Published online January 13 in Cancer Cell, the new work revolves around circular RNA, a recently described type of ribonucleic acid (RNA). Typically, DNA blueprints are converted into RNA and then into proteins with cellular functions. […]

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Prostate cancer can now be diagnosed better using artificial intelligence

Researchers at Radboud university medical center have developed a ‘deep learning’ system that is better than most pathologists at determining the aggressiveness of prostate cancer. The AI system, which uses tissue samples to arrive at its diagnosis, taught itself to identify prostate cancer based on data from over 1200 patients. The Radboud team is now working with researchers from the […]

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Smart algorithm finds possible future treatment for childhood cancer

Using a computer algorithm, scientists at Uppsala University have identified a promising new treatment for neuroblastoma. This form of cancer in children, which occurs in specialized nerve cells in the sympathetic nervous system, may be life-threatening. In the long term the discovery, described in the latest issue of the scientific journal Nature Communications, may result in a new form of […]

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New Insights: Armies of strategically stationed T cells fight viral infections, cancer

The immune system mounts robust responses to infections, vaccines and cancer, but only now have scientists fully begun to unravel how non-circulating populations of T cells that reside in the body’s “mucosal barrier tissues” keeps threats at bay. While an academic focus on non-circulating T cells in mucosal tissues may seem like an arcane area of research, it is the […]

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